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Chem Impex
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Product Information

Product Name
Fmoc-4-(phenoxy)-L-phenylalanine
Brand Name
Chem Impex
Product Number
29694
CAS
180414-93-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
16213186
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-phenoxyphenyl)propanoic acid
InChI Key
AREGUKFAPOBHGQ-NDEPHWFRSA-N
SMILES
C1=CC=C(C=C1)OC2=CC=C(C=C2)CC@@H(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

Application

Fmoc-4-(phenoxy)-L-phenylalanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.

Drug Development: Its unique structure makes it valuable in the design of peptide-based drugs, particularly in targeting specific biological pathways, enhancing therapeutic efficacy.

Bioconjugation: The compound is used in bioconjugation processes, where it helps attach peptides to other molecules, such as antibodies or drugs, improving delivery and targeting in therapeutic applications.

Research in Cancer Therapy: It plays a role in developing novel anticancer agents, as modifications of phenylalanine derivatives can lead to compounds that inhibit tumor growth.

Protein Engineering: Researchers utilize this compound in the modification of proteins, aiding in the study of protein interactions and functions, which is crucial for understanding various biological processes.

References

Solid phase synthesis of peptidyl aldehydes from C-terminal thiazolidinyl peptides

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 1997-12
DOI: 10.1007/bf02442913|10.1023/a:1008802417022