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Sku CI07184_5_G
Chem Impex
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Product Information

Product Name
Fmoc-pentafluoro-L-phenylalanine
Brand Name
Chem Impex
Product Number
07184
CAS
205526-32-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7020337
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(2,3,4,5,6-pentafluorophenyl)propanoic acid
InChI Key
DLOGILOIJKBYKA-KRWDZBQOSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CC4=C(C(=C(C(=C4F)F)F)F)F)C(=O)O

Description

Fmoc-pentafluoro-L-phenylalanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of fluorinated amino acids that enhance peptide stability and bioactivity.

Drug Development: Its unique fluorinated structure is beneficial in medicinal chemistry, where it can improve the pharmacokinetic properties of drug candidates, making them more effective and selective.

Bioconjugation: Researchers use this compound to create bioconjugates, which are essential in developing targeted therapies and diagnostic agents, particularly in cancer treatment.

Material Science: The fluorinated properties contribute to the development of advanced materials with improved chemical resistance and thermal stability, useful in coatings and electronics.

Research on Protein Folding: It aids in studies related to protein folding and stability, providing insights into protein interactions and functions, which is crucial for understanding various biological processes.