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Chem Impex
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Product Information

Product Name
Nim-Benzyl-L-histidine
Brand Name
Chem Impex
Product Number
06071
CAS
16832-24-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
193138
IUPAC Name
(2S)-2-amino-3-(1-benzylimidazol-4-yl)propanoic acid
InChI Key
NMXSWQMJOZUQKY-LBPRGKRZSA-N
SMILES
C1=CC=C(C=C1)CN2C=C(N=C2)CC@@H(C(=O)O)N

Application

Nim-Benzyl-L-histidine is widely utilized in research focused on:

Biochemical Research: This compound serves as a valuable tool in studying enzyme activity and protein interactions, particularly in the context of histidine-rich proteins.

Pharmaceutical Development: It is explored for its potential as a drug candidate, especially in targeting specific receptors or pathways in disease models.

Neuroscience: Researchers use it to investigate neurotransmitter systems, as it may influence synaptic transmission and neuroprotection.

Peptide Synthesis: Nim-Benzyl-L-histidine is employed in the synthesis of bioactive peptides, enhancing the specificity and efficacy of therapeutic agents.

Diagnostic Applications: Its unique properties make it a candidate for developing diagnostic tools that can detect specific biomarkers in various diseases.

References Data Source From Pubchem

l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2019-08-15
DOI: 10.1016/j.bmcl.2019.06.033

Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2018-07-26
DOI: 10.1021/acs.jmedchem.8b01007

Allosteric activation of HutP protein, that regulates transcription of hut operon in Bacillus subtilis, mediated by various analogs of histidine

Publication Name: Nucleic acids research. Supplement (2001)
Publication Date: 2003-09-01
DOI: 10.1093/nass/3.1.199

Two-dimensional crystallization of catalase on a monolayer film of poly(1-benzyl-l-histidine) spread at the air/water interface

Publication Name: Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
Publication Date: 1993-03-05
DOI: 10.1016/0167-4838(93)90127-d

3. GrenzflÄchenerscheinungen

Publication Name: Kolloid-Zeitschrift und Zeitschrift für Polymere
Publication Date: 1965
DOI: 10.1007/bf01499853