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Sku CI05998_25_G
Chem Impex
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Product Information

Product Name
D-Propargylglycine
Brand Name
Chem Impex
Product Number
05998
CAS
23235-03-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6992713
IUPAC Name
(2R)-2-aminopent-4-ynoic acid
InChI Key
DGYHPLMPMRKMPD-SCSAIBSYSA-N
SMILES
C#CCC@H(C(=O)O)N

Description

D-Propargylglycine is widely utilized in research focused on:

Neuropharmacology: This compound acts as an inhibitor of the enzyme cystathionine γ-lyase, which is involved in the production of hydrogen sulfide, a signaling molecule in the brain. Its application helps in studying neurodegenerative diseases and potential therapies.

Metabolic Studies: Researchers use D-Propargylglycine to investigate metabolic pathways involving sulfur-containing amino acids. This aids in understanding metabolic disorders and developing nutritional interventions.

Cardiovascular Research: The compound's role in modulating hydrogen sulfide levels makes it valuable for studying cardiovascular health, particularly in conditions like hypertension and heart failure.

Pharmaceutical Development: D-Propargylglycine serves as a lead compound in the synthesis of new drugs targeting various diseases, providing a scaffold for the development of novel therapeutic agents.

Biochemical Assays: It is commonly used in laboratory assays to measure enzyme activity related to sulfur metabolism, offering insights into various biochemical processes and disease mechanisms.