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Sku CI05755_5_G
Chem Impex
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Product Information

Product Name
Fmoc-4-fluoro-DL-phenylalanine
Brand Name
Chem Impex
Product Number
05755
CAS
264276-42-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2759191
IUPAC Name
2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-fluorophenyl)propanoic acid
InChI Key
IXUMACXMEZBPJG-UHFFFAOYSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CC=C(C=C4)F)C(=O)O

Description

Fmoc-4-fluoro-DL-phenylalanine is widely utilized in research focused on

Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of fluorinated amino acids that can enhance the stability and bioactivity of the resulting peptides.

Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing novel drugs, especially those targeting specific biological pathways where fluorine substitution can improve pharmacokinetics.

Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of peptides to other biomolecules, which is crucial for creating targeted therapies and diagnostic agents.

Research in Protein Engineering: Researchers utilize this compound to study protein folding and stability, as the fluorine atom can influence the interactions within protein structures, providing insights into protein behavior.

Fluorinated Compound Studies: It serves as a model compound in studies exploring the effects of fluorination on biological activity, helping scientists understand how modifications can lead to improved therapeutic profiles.