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Sku CI05536_1_G
Chem Impex
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Product Information

Product Name
Boc-L-glutamic acid a-9-fluorenylmethyl ester
Brand Name
Chem Impex
Product Number
05536
CAS
133906-29-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
131685
IUPAC Name
(4S)-5-(9H-fluoren-9-ylmethoxy)-4-(2-methylpropan-2-yl)oxycarbonylamino-5-oxopentanoic acid
InChI Key
KSYVYHUPZNONJS-FQEVSTJZSA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CCC(=O)O)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Description

Boc-L-glutamic acid a-9-fluorenylmethyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. This is crucial in developing complex peptides for pharmaceuticals.

Drug Development: Its application in medicinal chemistry helps in designing and optimizing drug candidates, particularly those targeting neurological disorders, by modifying amino acid sequences for improved efficacy.

Bioconjugation: The compound is used in bioconjugation processes, linking biomolecules such as proteins and antibodies to therapeutic agents, enhancing their delivery and effectiveness in targeted therapies.

Research in Protein Engineering: It aids in the modification of proteins, allowing researchers to study structure-function relationships, which is essential for developing new biocatalysts or therapeutic proteins.

Analytical Chemistry: The compound is utilized in various analytical techniques, such as HPLC, to separate and identify amino acids and peptides, providing valuable insights into biochemical processes.

References Data Source From Pubchem

Inverse Peptide Synthesis Using Transient Protected Amino Acids

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2025
DOI: 10.1007/978-1-0716-4562-8_21

Synthesis of beta- and gamma-fluorenylmethyl esters of respectively N alpha-Boc-L-aspartic acid and N alpha-Boc-L-glutamic acid

Publication Name: International Journal of Peptide and Protein Research
Publication Date: 1990-03
DOI: 10.1111/j.1399-3011.1990.tb00940.x