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Sku CI05315_25_G
Chem Impex
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Product Information

Product Name
Benzyl-L-proline
Brand Name
Chem Impex
Product Number
05315
CAS
31795-93-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
728719
IUPAC Name
(2S)-1-benzylpyrrolidine-2-carboxylic acid
InChI Key
XNROFTAJEGCDCT-NSHDSACASA-N
SMILES
C1CC@H(N(C1)CC2=CC=CC=C2)C(=O)O

Description

Benzyl-L-proline is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key building block in the synthesis of various pharmaceuticals, particularly in the development of analgesics and anti-inflammatory drugs.

Peptide Synthesis: It is frequently used in the synthesis of peptides, enhancing the stability and bioactivity of peptide-based drugs, which is crucial for therapeutic applications.

Chiral Catalysis: Benzyl-L-proline acts as a chiral auxiliary in asymmetric synthesis, allowing chemists to produce enantiomerically pure compounds, which are essential in drug development.

Neuroscience Research: The compound is studied for its potential effects on neurotransmitter systems, contributing to the understanding of neurological disorders and the development of related treatments.

Material Science: It is also explored in the creation of novel materials, such as polymers and hydrogels, which can be used in drug delivery systems and tissue engineering.

References Data Source From Pubchem

Synthesis of chiral pyrrolidine derivatives with promising pharmacological activity

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 2025-04
DOI: 10.1007/s10593-025-03405-8

Reductive Cleavage of Benzyl Esters

Publication Name: Science of Synthesis
Publication Date: 2024

Recyclable Copper-Catalyzed Decarboxylative C–C Coupling of the sp3-Hybridized Carbon Atoms of α-Amino Acids

Publication Name: Catalysis Letters
Publication Date: 2022-03-16
DOI: 10.1007/s10562-022-03936-1

Amino Acid Transporters and Exchangers from the SLC1A Family: Structure, Mechanism and Roles in Physiology and Cancer

Publication Name: Neurochemical Research
Publication Date: 2020-01-24
DOI: 10.1007/s11064-019-02934-x

Synthesis of Phosphaproline Derivatives: A Short Overview

Publication Name: Synthesis
Publication Date: 2019-07-15
DOI: 10.1055/s-0037-1611891