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Sku CI04992_25_G
Chem Impex
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Product Information

Product Name
Fmoc-3-nitro-L-tyrosine
Brand Name
Chem Impex
Product Number
04992
CAS
136590-09-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2756119
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxy-3-nitrophenyl)propanoic acid
InChI Key
JZUZJVFERQWLNC-FQEVSTJZSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CC4=CC(=C(C=C4)O)N+(=O)O-)C(=O)O

Description

Fmoc-3-nitro-L-tyrosine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of nitro groups that can be used for further modifications.

Drug Development: Its unique properties make it valuable in the design of novel pharmaceuticals, especially those targeting specific biological pathways, enhancing the effectiveness of drug candidates.

Bioconjugation: The nitro group can be selectively reduced, enabling the attachment of various biomolecules, which is crucial in creating targeted therapies and diagnostic tools in biomedicine.

Fluorescent Probes: This compound can be utilized in the development of fluorescent probes for imaging applications, aiding researchers in visualizing cellular processes in real-time.

Research in Neuroscience: Its structural similarity to neurotransmitters allows for studies in neurobiology, helping researchers understand receptor interactions and signaling pathways.

References Data Source From Pubchem

Synthesis of Molecularly Imprinted Polymers for Amino Acid Derivates by Using Different Functional Monomers

Publication Name: International Journal of Molecular Sciences
Publication Date: 2011-03-07
DOI: 10.3390/ijms12031735

On-Demand Cleavable Linkers for Radioimmunotherapy

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2009
DOI: 10.1007/978-1-60327-003-8_11

Addition of o-aminobenzoic acid during Fmoc solid phase synthesis of a fluorogenic substrate containing 3-nitrotyrosine

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2002-07
DOI: 10.1007/bf02538387|10.1023/a:1024141823692