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Sku CI04922_5_G
Chem Impex
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Product Information

Product Name
Boc-3-iodo-L-tyrosine
Brand Name
Chem Impex
Product Number
04922
CAS
71400-63-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
15545208
IUPAC Name
(2S)-3-(4-hydroxy-3-iodophenyl)-2-(2-methylpropan-2-yl)oxycarbonylaminopropanoic acid
InChI Key
VQTPRGZNDPHKOU-JTQLQIEISA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CC1=CC(=C(C=C1)O)I)C(=O)O

Description

Boc-3-iodo-L-tyrosine is widely utilized in research focused on

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of biologically active molecules. Its unique structure allows for the incorporation of iodine, which can enhance the properties of the resulting peptides.

Drug Development: In pharmaceutical research, Boc-3-iodo-L-tyrosine is used to create compounds that target specific biological pathways. Its ability to modify tyrosine residues can lead to improved drug efficacy and selectivity.

Radiolabeling Applications: The iodine atom in this compound makes it suitable for radiolabeling, which is crucial in imaging techniques like PET scans. This application is particularly valuable in oncology for tracking tumor growth.

Bioconjugation: This chemical can be employed in bioconjugation processes, where it is used to link biomolecules to other entities, such as drugs or imaging agents, enhancing their delivery and effectiveness in targeted therapies.

Research in Neuroscience: Its role in modifying neurotransmitter pathways makes it a valuable tool in neuroscience research, helping scientists understand the effects of tyrosine derivatives on brain function and behavior.

References Data Source From Pubchem

Total Synthesis of Mycocyclosin and the Herqulines

Publication Name: Synthesis
Publication Date: 2021-03-16
DOI: 10.1055/a-1403-4312

Functionalization of protected tyrosine via Sonogashira reaction: synthesis of 3-(1,2,3-triazolyl)-tyrosine

Publication Name: Molecular Diversity
Publication Date: 2015-10-26
DOI: 10.1007/s11030-015-9642-y