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Sku CI04502_250_MG
Chem Impex
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Product Information

Product Name
Benzoyl-L-tyrosine 4-nitroanilide
Brand Name
Chem Impex
Product Number
04502
CAS
6154-45-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
188992
IUPAC Name
N-(2S)-3-(4-hydroxyphenyl)-1-(4-nitroanilino)-1-oxopropan-2-ylbenzamide
InChI Key
CJERUMAUMMIPRF-FQEVSTJZSA-N
SMILES
C1=CC=C(C=C1)C(=O)NC@@H(CC2=CC=C(C=C2)O)C(=O)NC3=CC=C(C=C3)N+(=O)O-

Description

Benzoyl-L-tyrosine 4-nitroanilide is widely utilized in research focused on:

Biochemical Assays: This compound is often used as a substrate in enzyme assays, particularly for studying proteases. Its specificity allows researchers to accurately measure enzyme activity, which is crucial in drug development.

Drug Development: In pharmaceutical research, it serves as a model compound for designing inhibitors. Its structure helps in understanding how modifications can enhance drug efficacy and selectivity.

Diagnostic Applications: The compound can be employed in diagnostic kits for detecting specific enzyme activities related to various diseases, aiding in early diagnosis and treatment planning.

Research on Protein Interactions: It is used in studies investigating protein-ligand interactions, providing insights into molecular mechanisms that can lead to new therapeutic targets.

Educational Purposes: Benzoyl-L-tyrosine 4-nitroanilide is also utilized in academic laboratories for teaching purposes, helping students understand enzyme kinetics and molecular biology techniques.

References Data Source From Pubchem

Enzymatic Hydrolysis of N-Benzoyl-l-Tyrosine p-Nitroanilide by α-Chymotrypsin in DMSO-Water/AOT/n-Heptane Reverse Micelles. A Unique Interfacial Effect on the Enzymatic Activity

Publication Name: Langmuir : the ACS journal of surfaces and colloids
Publication Date: 2013-06-20
DOI: 10.1021/la401103q

Chymotrypsin immobilization on epoxy monolithic silica columns: Development and characterization of a bioreactor for protein digestion

Publication Name: Journal of Separation Science
Publication Date: 2007-11
DOI: 10.1002/jssc.200700337

Purification and characterization of a serine carboxypeptidase from Kluyveromyces marxianus

Publication Name: International Journal of Food Microbiology
Publication Date: 2004-03-15
DOI: 10.1016/s0168-1605(03)00409-4

Proteinases and exopeptidases from the phytopathogenic fungus Ustilago maydis

Publication Name: Mycologia
Publication Date: 2003-03
DOI: 10.1080/15572536.2004.11833118

Preliminary characterisation of digestive proteases of the green mirid, Creontiades dilutus (Hemiptera: Miridae)

Publication Name: Insect Biochemistry and Molecular Biology
Publication Date: 2001-03-15
DOI: 10.1016/s0965-1748(00)00136-3