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Sku CI04445_100_G
Chem Impex
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Product Information

Product Name
D-Proline amide
Brand Name
Chem Impex
Product Number
04445
CAS
62937-45-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
447554
IUPAC Name
(2R)-pyrrolidine-2-carboxamide
InChI Key
VLJNHYLEOZPXFW-SCSAIBSYSA-N
SMILES
C1CC@@H(NC1)C(=O)N

Description

D-Proline amide is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a building block in the synthesis of various pharmaceuticals, particularly in the development of peptide-based drugs, enhancing their efficacy and stability.

Biotechnology: It is used in the production of biocatalysts and enzyme inhibitors, which can improve reaction rates in biochemical processes, making it valuable in industrial biotechnology applications.

Protein Engineering: D-Proline amide plays a significant role in modifying protein structures, helping researchers design proteins with desired properties for therapeutic uses.

Material Science: It is incorporated into polymers and materials to enhance their mechanical properties, contributing to the development of stronger and more durable materials.

Research on Neurodegenerative Diseases: The compound is being investigated for its potential neuroprotective effects, offering hope for new treatments in conditions like Alzheimer's and Parkinson's disease.

References Data Source From Pubchem

Asymmetric formation of γ-lactams via C–H amidation enabled by chiral hydrogen-bond-donor catalysts

Publication Name: Nature Catalysis
Publication Date: 2019-02-18
DOI: 10.1038/s41929-019-0230-x

(R)-amidase 3.5.1.100

Publication Name: Class 3.4–6 Hydrolases, Lyases, Isomerases, Ligases
Publication Date: 2013
DOI: 10.1007/978-3-642-36260-6_11

L-proline amide hydrolase 3.5.1.101

Publication Name: Class 3.4–6 Hydrolases, Lyases, Isomerases, Ligases
Publication Date: 2013
DOI: 10.1007/978-3-642-36260-6_12

Effective asymmetric synthesis of the key chiral building blocks of 20(S)- and 20(R)-camptothecins

Publication Name: Monatshefte für Chemie - Chemical Monthly
Publication Date: 2011-09-07
DOI: 10.1007/s00706-011-0617-0

Synthesis of a Dimer of β-(1,4)-l-Arabinosyl-(2S,4R)-4-hydroxyproline Inspired by Art v 1, the Major Allergen of Mugwort

Publication Name: Organic Letters
Publication Date: 2010-10-11
DOI: 10.1021/ol102112z