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Chem Impex
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Product Information

Product Name
Na-Boc-L-tryptophan N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
04023
CAS
3392-11-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
98767
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) (2S)-3-(1H-indol-3-yl)-2-(2-methylpropan-2-yl)oxycarbonylaminopropanoate
InChI Key
CPJXMXQYRHNIFU-HNNXBMFYSA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CC1=CNC2=CC=CC=C21)C(=O)ON3C(=O)CCC3=O

Description

Na-Boc-L-tryptophan N-hydroxysuccinimide ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those involving tryptophan, enhancing the efficiency of the coupling reactions.

Drug Development: It plays a role in the development of pharmaceuticals, especially in creating compounds that target serotonin receptors, which are crucial for mood regulation.

Bioconjugation: The N-hydroxysuccinimide ester functionality allows for easy conjugation with various biomolecules, making it valuable in creating targeted drug delivery systems.

Research in Neuroscience: Its applications extend to neuroscience research, where it is used to study the effects of tryptophan derivatives on neurotransmitter pathways.

Protein Labeling: The compound can be used for labeling proteins, aiding in the visualization and tracking of protein interactions in biological studies.

References Data Source From Pubchem

Search for New Drugs for Treatment of Tuberculosis

Publication Name: Antimicrobial Agents and Chemotherapy
Publication Date: 2001-07
DOI: 10.1128/aac.45.7.1943-1946.2001

The regularities of the changes of amino acid physico-chemical properties within the genetic code

Publication Name: Amino Acids
Publication Date: 1995-03
DOI: 10.1007/bf00806539

A recombinant human stromelysin catalytic domain identifying tryptophan derivatives as human stromelysin inhibitors

Publication Name: Journal of Medicinal Chemistry
Publication Date: 1994-01-07
DOI: 10.1021/jm00027a027

Synthesis of conformationally constrained CCK-4 analogs containing a substituted gamma lactam ring

Publication Name: Peptides
Publication Date: 1988
DOI: 10.1007/978-94-010-9595-2_36