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Sku CI03939_1_G
Chem Impex
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Product Information

Product Name
Fmoc-O-dimethylphospho-L-tyrosine
Brand Name
Chem Impex
Product Number
03939
CAS
127633-36-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
9983850
IUPAC Name
(2S)-3-(4-dimethoxyphosphoryloxyphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
InChI Key
ZQHCDMSMVMNCER-DEOSSOPVSA-N
SMILES
COP(=O)(OC)OC1=CC=C(C=C1)CC@@H(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Description

Fmoc-O-dimethylphospho-L-tyrosine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a crucial building block in the synthesis of phosphotyrosine-containing peptides, which are important for studying protein interactions and signaling pathways.

Drug Development: It is used in the development of pharmaceuticals targeting tyrosine kinases, which play a significant role in cancer and other diseases, providing a pathway for innovative treatments.

Bioconjugation: The chemical is employed in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, enhancing the effectiveness of drug delivery systems.

Analytical Chemistry: It aids in the development of analytical methods for detecting and quantifying phosphotyrosine in biological samples, facilitating research in cellular signaling and disease mechanisms.

Biotechnology: This compound is utilized in various biotechnological applications, such as the design of biosensors that can detect specific proteins or enzymes, improving diagnostic capabilities.

References Data Source From Pubchem

N α-Fmoc-O, O-(dimethylphospho)-L-tyrosine fluoride: A convenient building block for the solid-phase synthesis of phosphotyrosyl peptides

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 1997-06
DOI: 10.1007/bf02443530|10.1023/a:1008806907085