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Sku CI03923_1_G
Chem Impex
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Product Information

Product Name
Fmoc-4-iodo-L-phenylalanine
Brand Name
Chem Impex
Product Number
03923
CAS
82565-68-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2761479
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-iodophenyl)propanoic acid
InChI Key
LXOXXTQKKRJNNB-QFIPXVFZSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CC4=CC=C(C=C4)I)C(=O)O

Application

Fmoc-4-iodo-L-phenylalanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific sequences and functionalities.

Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, particularly those targeting specific proteins or receptors.

Bioconjugation: The iodine atom in this compound facilitates bioconjugation, enabling the attachment of various biomolecules for applications in diagnostics and therapeutics.

Research in Cancer Therapeutics: The compound is being explored for its potential in cancer treatment, as it can be incorporated into peptides that selectively target cancer cells.

Fluorescent Labeling: Researchers use it for fluorescent labeling in studies involving protein interactions, enhancing the understanding of biological processes.

References

Applications of biaryl cyclization in the synthesis of cyclic enkephalin analogs with a highly restricted flexibility

Publication Name: Amino Acids
Publication Date: 2024-03-01
DOI: 10.1007/s00726-023-03371-5

Solid-Phase Synthesis of Biaryl Cyclic Peptides Containing a Histidine-Phenylalanine Linkage

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2019-06-19
DOI: 10.1007/s10989-019-09877-5

Efficient Scaled-Up Synthesis of N-α-Fmoc-4-Phosphono(difluoromethyl)-l-phenylalanine and Its Incorporation into Peptides

Publication Name: Synthesis
Publication Date: 2011-09-06
DOI: 10.1055/s-0030-1260206

Peptide model helices in lipid membranes: insertion, positioning, and lipid response on aggregation studied by X-ray scattering

Publication Name: European biophysics journal : EBJ
Publication Date: 2010-12-23
DOI: 10.1007/s00249-010-0645-4

Synthesis of Phosphopeptides in the Fmoc Mode

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2007-08-21
DOI: 10.1007/s10989-007-9107-y