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Sku CI03818_1_G
Chem Impex
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Product Information

Product Name
Boc-L-tyrosine N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
03818
CAS
20866-56-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
12790906
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) (2S)-3-(4-hydroxyphenyl)-2-(2-methylpropan-2-yl)oxycarbonylaminopropanoate
InChI Key
NZUDTLHVKHXJJJ-ZDUSSCGKSA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CC1=CC=C(C=C1)O)C(=O)ON2C(=O)CCC2=O

Description

Boc-L-tyrosine N-hydroxysuccinimide ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities, enhancing the development of therapeutic agents.

Drug Development: Its ability to modify amino acids makes it valuable in drug design, particularly in creating prodrugs that improve the bioavailability of active pharmaceutical ingredients.

Bioconjugation: The ester functionality facilitates the conjugation of biomolecules, which is crucial in developing targeted drug delivery systems and diagnostic tools in the biomedical field.

Research in Neuroscience: As a derivative of tyrosine, it plays a role in studying neurotransmitter pathways, aiding in the understanding of various neurological conditions and potential treatments.

Protein Engineering: It is used to introduce specific modifications in proteins, enhancing their stability and activity, which is essential for various applications in biotechnology and pharmaceuticals.

References Data Source From Pubchem

Kyotorphin analogues containing unnatural amino acids: synthesis, analgesic activity and computer modeling of their interactions with μ-receptor

Publication Name: Medicinal Chemistry Research
Publication Date: 2014-02-26
DOI: 10.1007/s00044-014-0953-9

Design of novel synthetic peptides including cyclic conformationally and topographically constrained analogs

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 1994
DOI: 10.1385/0-89603-273-6:201