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Chem Impex
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Product Information

Product Name
Boc-L-methionine N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
03803
CAS
3845-64-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
12876462
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) (2S)-2-(2-methylpropan-2-yl)oxycarbonylamino-4-methylsulfanylbutanoate
InChI Key
PCZJWSPKNYONIM-VIFPVBQESA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CCSC)C(=O)ON1C(=O)CCC1=O

Description

Boc-L-methionine N-hydroxysuccinimide ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as an effective building block in the synthesis of peptides, allowing researchers to create complex molecules with specific amino acid sequences for drug development and biological studies.

Bioconjugation: It is commonly used for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the functionality of diagnostic tools and therapeutic agents.

Drug Delivery Systems: The ester can be incorporated into drug delivery formulations, improving the stability and release profiles of therapeutic compounds, which is crucial for targeted therapies.

Research in Cancer Therapeutics: Its application in developing novel cancer treatments allows for the selective targeting of cancer cells, minimizing side effects on healthy tissues compared to traditional chemotherapeutics.

Protein Modification: Researchers utilize this compound to modify proteins, which can help in studying protein interactions and functions, leading to advancements in understanding various biological processes.

References Data Source From Pubchem

Chemoproteomic Profiling of Adenylation Domain Functions in Gramicidin S-Producing Non-ribosomal Peptide Synthetases

Publication Name: Non-Ribosomal Peptide Biosynthesis and Engineering
Publication Date: 2023
DOI: 10.1007/978-1-0716-3214-7_4

Conformational studies of chemotactic HCO-Met-Leu-Phe-OMe analogues

Publication Name: Amino Acids
Publication Date: 1995-12
DOI: 10.1007/bf00807274

Prerequisite for His(4) in deltorphin A for highδ opioid receptor selectivity

Publication Name: Amino Acids
Publication Date: 1994-10
DOI: 10.1007/bf00807704

Synthesis and biological activity of the reproductive α-factor of the yeastSaccharomyces cerevisiae and its DES-Trp1 analog

Publication Name: Pharmaceutical Chemistry Journal
Publication Date: 1982-10
DOI: 10.1007/bf00772161