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Sku CI03787_25_G
Chem Impex
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Product Information

Product Name
Boc-L-glutamic acid a-tert-butyl ester
Brand Name
Chem Impex
Product Number
03787
CAS
24277-39-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6993444
IUPAC Name
(4S)-5-(2-methylpropan-2-yl)oxy-4-(2-methylpropan-2-yl)oxycarbonylamino-5-oxopentanoic acid
InChI Key
YMOYURYWGUWMFM-VIFPVBQESA-N
SMILES
CC(C)(C)OC(=O)C@H(CCC(=O)O)NC(=O)OC(C)(C)C

Description

Boc-L-glutamic acid a-tert-butyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protecting group for amino acids during peptide synthesis, allowing for the selective modification of other functional groups without interfering with the glutamic acid residue.

Drug Development: It plays a crucial role in the design of pharmaceuticals, particularly in the development of prodrugs that enhance bioavailability and stability, making it easier to deliver therapeutic agents effectively.

Biotechnology: In the field of biotechnology, it is used in the production of peptide-based vaccines, where the protected amino acid can be incorporated into larger peptide chains to elicit immune responses.

Research in Neuroscience: The compound is valuable in neuroscience research for studying glutamate receptors, which are essential for synaptic transmission and plasticity, providing insights into neurological disorders.

Analytical Chemistry: It is employed in analytical methods to identify and quantify amino acids in complex mixtures, aiding researchers in characterizing biological samples and understanding metabolic pathways.

References Data Source From Pubchem

Modular alkene synthesis from carboxylic acids, alcohols and alkanes via integrated photocatalysis

Publication Name: Nature Chemistry
Publication Date: 2024-09-27
DOI: 10.1038/s41557-024-01642-6

Research on GGT-responsive drug carrier with active transport effect

Publication Name: Nano Research
Publication Date: 2023-01-03
DOI: 10.1007/s12274-022-5264-8

Synthesis of Tryptophan–Folate Conjugates

Publication Name: Synlett
Publication Date: 2020-02-26
DOI: 10.1055/s-0039-1691735

Influx rate of 18F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts

Publication Name: European Journal of Nuclear Medicine and Molecular Imaging
Publication Date: 2019-07-01
DOI: 10.1007/s00259-019-04375-8

Supramolecular protein glue to boost enzyme activity

Publication Name: Science China Materials
Publication Date: 2019-04-17
DOI: 10.1007/s40843-019-9425-6