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Sku CI03760_100_MG
Chem Impex
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Product Information

Product Name
Fmoc-3-(2'-quinolyl)-D-alanine
Brand Name
Chem Impex
Product Number
03760
CAS
214852-58-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
56777165
IUPAC Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-quinolin-2-ylpropanoic acid
InChI Key
IDOMHXAHHXHYMO-RUZDIDTESA-N
SMILES
C1=CC=C2C(=C1)C=CC(=N2)CC@H(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

Description

Fmoc-3-(2'-quinolyl)-D-alanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.

Drug Development: Its unique structure enhances the bioactivity of peptide-based drugs, making it valuable in the pharmaceutical industry for developing new therapeutics.

Bioconjugation: The compound can be used to create bioconjugates, linking peptides to other biomolecules, which is crucial in the development of targeted drug delivery systems.

Fluorescent Probes: Due to its quinoline moiety, it can be utilized in the design of fluorescent probes for biological imaging, aiding researchers in visualizing cellular processes.

Research on Protein Interactions: It is beneficial in studying protein-ligand interactions, providing insights into molecular mechanisms that can lead to advancements in biotechnology and molecular biology.

References Data Source From Pubchem

Identification of inhibitors of the E. coli chaperone SurA using in silico and in vitro techniques

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2018-12-01
DOI: 10.1016/j.bmcl.2018.09.034