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Sku CI03677_1_G
Chem Impex
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Product Information

Product Name
Boc-L-proline N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
03677
CAS
3392-10-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
853883
IUPAC Name
1-O-tert-butyl 2-O-(2,5-dioxopyrrolidin-1-yl) (2S)-pyrrolidine-1,2-dicarboxylate
InChI Key
DICWIJISMKZDDY-VIFPVBQESA-N
SMILES
CC(C)(C)OC(=O)N1CCCC@H1C(=O)ON2C(=O)CCC2=O

Description

Boc-L-proline N-hydroxysuccinimide ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing researchers to create complex structures with high specificity and efficiency.

Drug Development: It plays a crucial role in the development of pharmaceuticals, particularly in designing prodrugs that enhance bioavailability and therapeutic efficacy.

Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.

Protein Modification: Researchers utilize this ester for modifying proteins, enabling the study of protein interactions and functions, which is vital in understanding various biological processes.

Research in Material Science: It is applied in the development of new materials, particularly those that require specific chemical functionalities, enhancing the performance of polymers and coatings.

References Data Source From Pubchem

Chemoproteomic Profiling of Adenylation Domain Functions in Gramicidin S-Producing Non-ribosomal Peptide Synthetases

Publication Name: Non-Ribosomal Peptide Biosynthesis and Engineering
Publication Date: 2023
DOI: 10.1007/978-1-0716-3214-7_4

Molecular design, synthesis and neuroleptic activity of dipeptide analogs of sulpride

Publication Name: Pharmaceutical Chemistry Journal
Publication Date: 1997-11
DOI: 10.1007/bf02464272

Syntheses of H-Arg202-Gly-Pro-Phe-Pro-Ile-Ile-Val209-OH, corresponding to the C-terminal portion of β-casein, and its analogs

Publication Name: Peptide Chemistry 1992
Publication Date: 1993
DOI: 10.1007/978-94-011-1474-5_125

Macroheterocycles. IV. Synthesis and analogesic activity of crown ethers containing leu-enkephalin and thyroliberin groups

Publication Name: Pharmaceutical Chemistry Journal
Publication Date: 1992-05
DOI: 10.1007/bf00772913