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Sku CI03132_5_G
Chem Impex
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Product Information

Product Name
L-Proline tert-butyl ester
Brand Name
Chem Impex
Product Number
03132
CAS
2812-46-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6453108
IUPAC Name
tert-butyl (2S)-pyrrolidine-2-carboxylate
InChI Key
XJJBXZIKXFOMLP-ZETCQYMHSA-N
SMILES
CC(C)(C)OC(=O)C@@H1CCCN1

Description

L-Proline tert-butyl ester is widely utilized in research focused on:

Synthesis of Peptides: This compound serves as a valuable building block in peptide synthesis, allowing researchers to create specific sequences for pharmaceuticals and biologically active compounds.

Chiral Auxiliary in Organic Reactions: It acts as a chiral auxiliary, enhancing the selectivity of reactions in asymmetric synthesis, which is crucial for producing enantiomerically pure compounds in medicinal chemistry.

Drug Development: The ester form improves the solubility and bioavailability of proline derivatives, making it beneficial in the formulation of new drugs.

Biochemical Research: It is used in studies involving protein folding and enzyme activity, helping scientists understand the role of proline in biological systems.

Material Science: This compound is explored for its potential in developing new polymers and materials due to its unique structural properties.

References Data Source From Pubchem

Application of Electrochemical Cross-Dehydrogenative Couplings in the Syntheses of Heterocycles

Publication Name: Heterocycles via Cross Dehydrogenative Coupling
Publication Date: 2019
DOI: 10.1007/978-981-13-9144-6_13

Structure elucidation of metabolite x17299 by interpretation of mass spectrometric data

Publication Name: Metabolomics : Official journal of the Metabolomic Society
Publication Date: 2017-06-24
DOI: 10.1007/s11306-017-1231-x

Proline Methanologues: Design, Synthesis, Structural Properties, and Applications in Medicinal Chemistry

Publication Name: Topics in Heterocyclic Chemistry
Publication Date: 2015
DOI: 10.1007/7081_2015_191