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Chem Impex
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Product Information

Product Name
Fmoc-b-cyclohexyl-L-alanine
Brand Name
Chem Impex
Product Number
02375
CAS
135673-97-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
978326
IUPAC Name
(2S)-3-cyclohexyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
InChI Key
HIJAUEZBPWTKIV-QFIPXVFZSA-N
SMILES
C1CCC(CC1)CC@@H(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Application

Fmoc-b-cyclohexyl-L-alanine is widely utilized in research focused on

Peptide Synthesis: This compound is commonly used as a building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.

Drug Development: Its unique structure makes it valuable in the design of peptide-based drugs, particularly in targeting specific biological pathways, enhancing therapeutic efficacy.

Bioconjugation: The Fmoc group enables easy attachment to various biomolecules, facilitating the development of bioconjugates for targeted drug delivery systems.

Research in Neuroscience: This compound is utilized in studies related to neuropeptides, contributing to the understanding of neurological functions and potential treatments for neurodegenerative diseases.

Custom Peptide Libraries: It serves as a key component in creating diverse peptide libraries for high-throughput screening, aiding in the discovery of new bioactive compounds.

References

Rapid de novo discovery of peptidomimetic affinity reagents for human angiotensin converting enzyme 2

Publication Name: Communications Chemistry
Publication Date: 2022-01-19
DOI: 10.1038/s42004-022-00625-3

Sequence-Specific Control of Mitochondrial Gene TranscriptionMitochondrial gene transcription Using Programmable Synthetic Gene Switches Called MITO-PIPs

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2021
DOI: 10.1007/978-1-0716-1262-0_13

Peptidomimetic Synthesis: Drug Discovery for Alzheimer’s Disease

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2020
DOI: 10.1007/978-1-0716-0227-0_14

Design, Synthesis, and Application of OB2C Combinatorial Peptide and Peptidomimetic Libraries

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2015
DOI: 10.1007/978-1-4939-2020-4_1

Development of Novel Peptides for Mitochondrial Drug Delivery: Amino Acids Featuring Delocalized Lipophilic Cations

Publication Name: Pharmaceutical Research
Publication Date: 2011-08-11
DOI: 10.1007/s11095-011-0530-6