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Chem Impex
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Product Information

Product Name
N,N'-Disuccinimidyl carbonate
Brand Name
Chem Impex
Product Number
02309
CAS
74124-79-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
676246
IUPAC Name
bis(2,5-dioxopyrrolidin-1-yl) carbonate
InChI Key
PFYXSUNOLOJMDX-UHFFFAOYSA-N
SMILES
C1CC(=O)N(C1=O)OC(=O)ON2C(=O)CCC2=O

Description

N,N'-Disuccinimidyl carbonate is widely utilized in research focused on:

Bioconjugation: This compound serves as a versatile crosslinker for attaching biomolecules, such as proteins and antibodies, to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.

Vaccine Development: It plays a crucial role in the formulation of vaccines by facilitating the conjugation of antigens to carrier proteins, improving immune response and stability.

Drug Delivery Systems: Researchers use it to create advanced drug delivery systems that allow for controlled release of therapeutics, increasing efficacy while minimizing side effects.

Protein Engineering: The compound is employed in the modification of proteins to study their structure and function, aiding in the design of novel enzymes and therapeutic proteins.

Diagnostics: It is utilized in the development of diagnostic assays, where it helps in the immobilization of biomolecules on solid supports, enhancing sensitivity and specificity in detection methods.

References Data Source From Pubchem

Derivatization agents for LC-MS analysis of amino acids: effects of core structure and functional groups

Publication Name: Analytical and Bioanalytical Chemistry
Publication Date: 2026-02-10
DOI: 10.1007/s00216-026-06366-9

Synthetic Strategies for Di-, Oligo-, and Polysialic Acids with Applications as Siglec Ligands

Publication Name: Chemical Biology of Carbohydrates
Publication Date: 2026
DOI: 10.1007/978-981-95-5335-8_3

Photonic resonator absorption microscopy: why consider metallic and magneto-plasmonic nano-assemblies over bare nanoparticles for digital biosensing?

Publication Name: Analytical and Bioanalytical Chemistry
Publication Date: 2025-08-30
DOI: 10.1007/s00216-025-06056-y

Direct cytosolic delivery of antigenic proteins via phospholipid polymer bioconjugates

Publication Name: Polymer Journal
Publication Date: 2025-07-31
DOI: 10.1038/s41428-025-01073-1