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Sku CI00766_5_KG
Chem Impex
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Product Information

Product Name
D(+)-Trehalose dihydrate
Brand Name
Chem Impex
Product Number
00766
CAS
6138-23-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
181978
IUPAC Name
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yloxyoxane-3,4,5-triol;dihydrate
InChI Key
DPVHGFAJLZWDOC-PVXXTIHASA-N
SMILES
C(C@@H1C@H(C@@H(C@H(C@H(O1)OC@@H2C@@H(C@H(C@@H(C@H(O2)CO)O)O)O)O)O)O)O.O.O

Description

D(+)-Trehalose dihydrate is widely utilized in research focused on:

Pharmaceuticals: It serves as a stabilizing agent for proteins and vaccines, enhancing their shelf life and efficacy. This is particularly beneficial in the development of biopharmaceuticals, where maintaining protein integrity is crucial.

Food Industry: Used as a natural sweetener and preservative, it helps retain moisture in baked goods and extends the shelf life of various food products without altering flavor, making it a popular choice among food manufacturers.

Cosmetics: Its moisturizing properties make it an excellent ingredient in skincare products, helping to improve skin hydration and texture, which is appealing to cosmetic formulators aiming for high-quality products.

Biotechnology: In cell culture, it acts as a cryoprotectant, protecting cells during freezing and thawing processes, which is essential for preserving cell lines and biological samples in research laboratories.

Neuroscience: Research indicates that it may have neuroprotective effects, making it a candidate for studies related to neurodegenerative diseases, providing hope for new therapeutic approaches.

FAQ

Q1: What is D-(+)-Trehalose Dihydrate?

A: D-(+)-Trehalose Dihydrate (CAS No. 6138-23-4) is a naturally occurring non-reducing disaccharide used as a stabilizer and protective agent for biological materials.

 

Q2: What is Trehalose Dihydrate used for?

A: It is mainly used in:

  • Protein stabilization
  • Vaccine formulation
  • Lyophilization
  • Cell preservation
  • Pharmaceutical excipient research
  • Cosmetic formulations

 

Q3: Why is Trehalose used in protein stabilization?

A: Trehalose forms hydrogen-bond interactions with biomolecules and helps maintain protein structure during dehydration, freezing, and storage.

 

Q4: What is the difference between Trehalose and sucrose?

Property Trehalose Sucrose
Structure Two glucose units Glucose + fructose
Reducing Ability Non-reducing Non-reducing
Stability Higher stability Lower stability
Protein Protection Strong Moderate

 

Q5: Is Trehalose used in vaccine formulations?

A: Yes. Trehalose is widely studied as a stabilizer for vaccines and biologics because it helps protect proteins during freeze-drying and storage.

 

Q6: Can Trehalose protect cells during freezing?

A: Yes. Trehalose is commonly used as a cryoprotective compound to reduce damage caused by freezing and dehydration.

 

Q7: Why is Trehalose suitable for cosmetics?

A: Its strong water-binding ability helps maintain moisture and protect skin cells from environmental stress.

 

Q8: How should Trehalose Dihydrate be stored?

A: Store in a sealed container under dry conditions and protect from humidity to maintain product quality.