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Chem Impex
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Product Information

Product Name
Na-Fmoc-Nim-trityl-L-histidine
Brand Name
Chem Impex
Product Number
00713
CAS
109425-51-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11422193
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-tritylimidazol-4-yl)propanoic acid
InChI Key
XXMYDXUIZKNHDT-QNGWXLTQSA-N
SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)N4C=C(N=C4)CC@@H(C(=O)O)NC(=O)OCC5C6=CC=CC=C6C7=CC=CC=C57

Application

Na-Fmoc-Nim-trityl-L-histidine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides with specific sequences.

Drug Development: It plays a significant role in pharmaceutical research, particularly in the development of peptide-based drugs, due to its ability to enhance stability and bioavailability of therapeutic peptides.

Bioconjugation: The compound is used in bioconjugation techniques, where it helps to attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.

Research in Cancer Therapy: Its applications extend to cancer research, where it is utilized in the design of peptide-based inhibitors that can selectively target cancer cells, improving treatment efficacy.

Protein Engineering: This chemical is valuable in protein engineering, aiding researchers in modifying proteins to enhance their function or stability, which is crucial for various biotechnological applications.

References Data Source From Pubchem

A bioinformatics approach to design minimal biomimetic metal-binding peptides

Publication Name: Communications Chemistry
Publication Date: 2025-10-06
DOI: 10.1038/s42004-025-01702-z

Genetic variance in the murine defensin locus modulates glucose homeostasis

Publication Name: The EMBO Journal
Publication Date: 2025-09-09
DOI: 10.1038/s44318-025-00555-5

Design and Evaluation of ATN-161 Analogues as Fusion Inhibitors Targeting Integrins in SARS-CoV-2

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2025-05-30
DOI: 10.1007/s10989-025-10734-x

Stabilization of a miniprotein fold by an unpuckered proline surrogate

Publication Name: Communications Chemistry
Publication Date: 2025-03-12
DOI: 10.1038/s42004-025-01474-6

Rapid peptide synthesis using a methylimidazolium sulfinyl fluoride salt

Publication Name: Communications Chemistry
Publication Date: 2025-02-22
DOI: 10.1038/s42004-025-01456-8