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Sku CI00289_100_G
Chem Impex
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Product Information

Product Name
Trifluoroacetic acid
Brand Name
Chem Impex
Product Number
00289
CAS
76-05-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6422
IUPAC Name
2,2,2-trifluoroacetic acid
InChI Key
DTQVDTLACAAQTR-UHFFFAOYSA-N
SMILES
C(=O)(C(F)(F)F)O

Application

Trifluoroacetic acid is widely utilized in research focused on:

Organic Synthesis: It serves as a powerful reagent in the synthesis of various organic compounds, enabling the introduction of trifluoromethyl groups which enhance the biological activity of pharmaceuticals.

Peptide Chemistry: This compound is commonly used in peptide synthesis, particularly in the protection and deprotection of amino acids, making it essential for developing new therapeutic peptides.

Analytical Chemistry: Trifluoroacetic acid is employed as a solvent and reagent in chromatography, improving the separation and analysis of complex mixtures in laboratories.

Environmental Studies: It is utilized in the study of environmental pollutants, aiding in the analysis of fluorinated compounds in various samples, which is crucial for assessing ecological impacts.

Pharmaceutical Formulations: The compound is used in the formulation of certain drugs, enhancing their stability and bioavailability, which is vital for effective medication delivery.

References Data Source From Pubchem

In vitro assessment of antioxidant, hypocholesterolemic and alpha-amylase inhibition of Lactiplantibacillus plantarum strains from a fermented Algerian milk

Publication Name: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
Publication Date: 2026-05-26
DOI: 10.1007/s42770-025-01856-x|10.1007/s42770-026-01946-4

Correction to: Quality by Design (QbD) Assisted HPLC Method for Concurrent Estimation of Aloe-Emodin and Adapalene

Publication Name: Journal of Pharmaceutical Innovation
Publication Date: 2026-05-11
DOI: 10.1007/s12247-026-10429-w|10.1007/s12247-026-10650-7

Author Correction: Strong and recyclable bio-derived poly(ester amide) hot-melt adhesive

Publication Name: Nature Sustainability
Publication Date: 2026-03-25
DOI: 10.1038/s41893-026-01776-0|10.1038/s41893-026-01904-w

AND logic nanoparticle for precision immunotherapy of metastatic cancers

Publication Name: Nature Nanotechnology
Publication Date: 2026-03-09
DOI: 10.1038/s41565-026-02130-3

Total Chemical Synthesis and Evaluation of the Antimicrobial Properties of Porcine β-Defensin 5 Against Gram-Positive and Gram-Negative Bacteria

Publication Name: Probiotics and Antimicrobial Proteins
Publication Date: 2026-03-04
DOI: 10.1007/s12602-025-10870-2