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Product Information

Product Name
N,N'-Diisopropylcarbodiimide
Brand Name
Chem Impex
Product Number
00110
CAS
693-13-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
12734
IUPAC Name
N,N'-di(propan-2-yl)methanediimine
InChI Key
BDNKZNFMNDZQMI-UHFFFAOYSA-N
SMILES
CC(C)N=C=NC(C)C

Application

N,N'-Diisopropylcarbodiimide is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a coupling agent in the formation of peptide bonds, making it essential for synthesizing peptides in pharmaceutical research.

Carboxylic Acid Activation: It effectively activates carboxylic acids for subsequent reactions, streamlining processes in organic synthesis and enhancing yield.

Bioconjugation: Used in bioconjugation techniques, it facilitates the attachment of biomolecules, which is crucial in developing targeted drug delivery systems.

Polymer Chemistry: It plays a significant role in creating polyurethanes and other polymers, contributing to advancements in materials science.

Cross-Linking Agents: This compound is employed as a cross-linking agent in various applications, improving the mechanical properties of materials in industries such as coatings and adhesives.

References

Artificial intelligence-guided design of lipid nanoparticles for pulmonary gene therapy

Publication Name: Nature Biotechnology
Publication Date: 2024-12-10
DOI: 10.1038/s41587-024-02490-y

Synthetic Studies of the Mutant Proinsulin Syndrome Demonstrate Correlation Between Folding Efficiency and Age of Diabetes Onset

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2024-11-20
DOI: 10.1007/s10989-024-10665-z

An ANN based modelling, forecasting, and experimental study of emissions and performance parameters running on microalgae biodiesel-nanoparticles blended fuel

Publication Name: Environment, Development and Sustainability
Publication Date: 2024-11-01
DOI: 10.1007/s10668-024-05548-8

O-GlcNAcylation of circadian clock protein Bmal1 impairs cognitive function in diabetic mice

Publication Name: The EMBO Journal
Publication Date: 2024-10-07
DOI: 10.1038/s44318-024-00263-6

Attaining improved control over the start of combustion in dual-fuel HCCI engine through the influence of EGR

Publication Name: Journal of Thermal Analysis and Calorimetry
Publication Date: 2024-10-07
DOI: 10.1007/s10973-024-13690-8