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Product Information

Product Name
N,N-Carbonyldiimidazole
Brand Name
Chem Impex
Product Number
00051
CAS
530-62-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
68263
IUPAC Name
di(imidazol-1-yl)methanone
InChI Key
PFKFTWBEEFSNDU-UHFFFAOYSA-N
SMILES
C1=CN(C=N1)C(=O)N2C=CN=C2

Application

N,N-Carbonyldiimidazole is widely utilized in research focused on:

Peptide Synthesis: This compound serves as an effective coupling agent in the formation of peptide bonds, facilitating the synthesis of peptides in pharmaceutical research.

Carbamate Formation: It is commonly used to convert alcohols into carbamates, which are important intermediates in the production of various agrochemicals and pharmaceuticals.

Protein Modification: Researchers employ it for selective modification of amino acids in proteins, enhancing the study of protein function and interactions.

Organic Synthesis: The compound acts as a versatile reagent in organic synthesis, particularly in the preparation of imidazole derivatives, which are valuable in medicinal chemistry.

Bioconjugation: It is utilized in bioconjugation processes to link biomolecules, aiding in the development of targeted drug delivery systems and diagnostic tools.

References Data Source From Pubchem

Chemoselective Probes for Profiling of Carboxylic Acid Metabolites in Biological Tissue

Publication Name: Chromatographia
Publication Date: 2026-03-04
DOI: 10.1007/s10337-026-04485-0

Photoredox N-heterocyclic carbene catalysis via radicals

Publication Name: Science China Chemistry
Publication Date: 2026-02-28
DOI: 10.1007/s11426-025-3107-4

From mortars to mills: mechanochemistry as a tool for efficient organic transformations

Publication Name: Journal of the Iranian Chemical Society
Publication Date: 2026-02-26
DOI: 10.1007/s13738-026-03381-6

Synthesis, QSAR analysis and molecular docking study of a new series of 3-hydroxypyridine-4-one derivatives as anti-tyrosinase agents

Publication Name: BMC Chemistry
Publication Date: 2026-01-29
DOI: 10.1186/s13065-025-01709-6

Structurally Modified Cyclodextrins in Topical Nanotechnology: Advancing Barrier-Penetrating Drug Delivery Strategies for Psoriasis Management

Publication Name: AAPS PharmSciTech
Publication Date: 2026-01-23
DOI: 10.1208/s12249-025-03309-y