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Product Information

Product Name
Na-Boc-Nw-4-toluenesulfonyl-L-arginine
Brand Name
Chem Impex
Product Number
00035
CAS
13836-37-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
83767
IUPAC Name
(2S)-5-amino-(4-methylphenyl)sulfonylaminomethylideneamino-2-(2-methylpropan-2-yl)oxycarbonylaminopentanoic acid
InChI Key
WBIIPXYJAMICNU-AWEZNQCLSA-N
SMILES
CC1=CC=C(C=C1)S(=O)(=O)NC(=NCCCC@@H(C(=O)O)NC(=O)OC(C)(C)C)N

Application

Na-Boc-Nw-4-toluenesulfonyl-L-arginine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interference from other functional groups. This is particularly beneficial in the pharmaceutical industry for creating complex peptide-based drugs.

Bioconjugation: It is used in bioconjugation processes, where biomolecules are linked to other molecules, enhancing the development of targeted drug delivery systems. This application is crucial in the field of biotechnology and personalized medicine.

Enzyme Inhibition Studies: Researchers utilize this compound to study enzyme inhibition mechanisms, providing insights into metabolic pathways and potential therapeutic targets, which is vital for drug discovery.

Diagnostic Reagents: The compound can be employed as a reagent in diagnostic tests, particularly in assays that require specific binding interactions, thus improving the accuracy of medical diagnostics.

Research on Protein Interactions: It aids in the investigation of protein-protein interactions, helping scientists understand cellular processes and disease mechanisms, which is essential for developing new therapeutic strategies.

References Data Source From Pubchem

Preparation and Characterization of pH-Responsive Charge Reversal Nanocomposite for miRNA Delivery

Publication Name: Journal of Wuhan University of Technology-Mater. Sci. Ed.
Publication Date: 2024-07-05
DOI: 10.1007/s11595-024-2969-4

Metformin booster adipocyte-targeted gene therapy for the treatment of obesity and related metabolic syndromes

Publication Name: Science China Chemistry
Publication Date: 2022-02-18
DOI: 10.1007/s11426-021-1185-2

In Situ Neutralization Protocols for Boc-SPPS

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2020
DOI: 10.1007/978-1-0716-0227-0_3

Semisynthesis of Membrane-Attached Proteins Using Split Inteins

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2017
DOI: 10.1007/978-1-4939-6451-2_7

Application of Circular Dichroism Spectroscopy to the Analysis of the Interaction Between the Estrogen Receptor Alpha and Coactivators: The Case of Calmodulin

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2016
DOI: 10.1007/978-1-4939-3127-9_19