Topotecan Hydrochloride, 98%, a Topoisomerase I inhibitor with potent antineoplastic activities

Name: Topotecan Hydrochloride, 98%, a Topoisomerase I inhibitor with potent antineoplastic activities | 119413-54-6
Brand: J&K Chemical
SKU: JK984758_50_MG
Price: 130.2 USD
Availability: OutOfStock

Cat. No JK984758_50_MG

Vendor: J&K Chemical

Product Information

Product Name

Topotecan Hydrochloride, 98%, a Topoisomerase I inhibitor with potent antineoplastic activities

Brand Name

J&K

Product Number

984758

CAS

119413-54-6

SDS Document

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Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

60699

IUPAC Name

(19S)-8-(dimethylamino)methyl-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo11.8.0.02,11.04,9.015,20henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride

InChI Key

DGHHQBMTXTWTJV-BQAIUKQQSA-N

SMILES

CCC@@1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

In Situ-Forming Hydrogels for Intratumoral Drug Delivery

Publication Name: In Situ Gellable Hydrogels for Drug Delivery and Tissue Engineering

Publication Date: 2026

DOI: 10.1007/978-981-95-6619-8_7

Frontotemporal dementia patient-derived iPSC neurons show cell pathological hallmarks and evidence for synaptic dysfunction and DNA damage

Publication Name: Molecular Psychiatry

Publication Date: 2025-09-26

DOI: 10.1038/s41380-025-03272-x

Non-coding RNAs’ pivotal importance in modulation of cancer sensitivity to Topotecan: a systematic review

Publication Name: Medical oncology (Northwood, London, England)

Publication Date: 2025-09-13

DOI: 10.1007/s12032-025-03029-0

RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids

Publication Name: Cancer Chemotherapy and Pharmacology

Publication Date: 2025-09-12

DOI: 10.1007/s00280-025-04800-w

Antiproliferative activities of phytochemicals isolated from the leaves of Dolichos kilimandischaricus (Harms) ex Taub. (Fabaceae) on Jurkat and HL-60 leukemic cells

Publication Name: BMC Complementary Medicine and Therapies

Publication Date: 2025-07-02

DOI: 10.1186/s12906-025-04977-w

Topotecan Hydrochloride, 98%, a Topoisomerase I inhibitor with potent antineoplastic activities

Product Information

General Information

Safety Information

References Data Source From Pubchem

In Situ-Forming Hydrogels for Intratumoral Drug Delivery

Frontotemporal dementia patient-derived iPSC neurons show cell pathological hallmarks and evidence for synaptic dysfunction and DNA damage

Non-coding RNAs’ pivotal importance in modulation of cancer sensitivity to Topotecan: a systematic review

RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids

Antiproliferative activities of phytochemicals isolated from the leaves of Dolichos kilimandischaricus (Harms) ex Taub. (Fabaceae) on Jurkat and HL-60 leukemic cells