PJ34 Hydrochloride, 97%, an inhibitor of PARPl1/2 with IC50 of 110 nM and 86 nM, respectively.

Name: PJ34 Hydrochloride, 97%, an inhibitor of PARPl1/2 with IC50 of 110 nM and 86 nM, respectively. | 344458-15-7
Brand: J&K Chemical
SKU: JK968129_50_MG
Price: 193.8 USD
Availability: OutOfStock

Cat. No JK968129_50_MG

Vendor: J&K Chemical

Product Information

Product Name

PJ34 Hydrochloride, 97%, an inhibitor of PARPl1/2 with IC50 of 110 nM and 86 nM, respectively.

Brand Name

J&K

Product Number

968129

CAS

344458-15-7

SDS Document

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Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

16760621

IUPAC Name

2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide;hydrochloride

InChI Key

RURAZZMDMNRXMI-UHFFFAOYSA-N

SMILES

CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors

Publication Name: Acta Pharmacologica Sinica

Publication Date: 2021-04-27

DOI: 10.1038/s41401-021-00668-7

Synergistic effects of type I PRMT and PARP inhibitors against non-small cell lung cancer cells

Publication Name: Clinical Epigenetics

Publication Date: 2021-03-10

DOI: 10.1186/s13148-021-01037-1

Improved Reperfusion and Vasculoprotection by the Poly(ADP-Ribose)Polymerase Inhibitor PJ34 After Stroke and Thrombolysis in Mice

Publication Name: Molecular Neurobiology

Publication Date: 2018-04-12

DOI: 10.1007/s12035-018-1063-3

Alpha-synuclein alters differently gene expression of Sirts, PARPs and other stress response proteins: implications for neurodegenerative disorders

Publication Name: Molecular Neurobiology

Publication Date: 2017-01-03

DOI: 10.1007/s12035-016-0317-1

PARP Inhibition Delays Progression of Mitochondrial Encephalopathy in Mice

Publication Name: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Publication Date: 2014-06-17

DOI: 10.1007/s13311-014-0285-y

PJ34 Hydrochloride, 97%, an inhibitor of PARPl1/2 with IC50 of 110 nM and 86 nM, respectively.

Product Information

General Information

Safety Information

References Data Source From Pubchem

A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors

Synergistic effects of type I PRMT and PARP inhibitors against non-small cell lung cancer cells

Improved Reperfusion and Vasculoprotection by the Poly(ADP-Ribose)Polymerase Inhibitor PJ34 After Stroke and Thrombolysis in Mice

Alpha-synuclein alters differently gene expression of Sirts, PARPs and other stress response proteins: implications for neurodegenerative disorders

PARP Inhibition Delays Progression of Mitochondrial Encephalopathy in Mice