WP1066, 98%, a novel inhibitor of JAK2 and STAT3

Name: WP1066, 98%, a novel inhibitor of JAK2 and STAT3 | 857064-38-1
Brand: J&K Chemical
SKU: JK930465_50_MG
Price: 379.3 USD
Availability: OutOfStock

Cat. No JK930465_50_MG

Vendor: J&K Chemical

Product Information

Product Name

WP1066, 98%, a novel inhibitor of JAK2 and STAT3

Brand Name

J&K

Product Number

930465

CAS

857064-38-1

SDS Document

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Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

11210478

IUPAC Name

(E)-3-(6-bromo-2-pyridinyl)-2-cyano-N-(1S)-1-phenylethylprop-2-enamide

InChI Key

VFUAJMPDXIRPKO-LQELWAHVSA-N

SMILES

CC@@H(C1=CC=CC=C1)NC(=O)/C(=C/C2=NC(=CC=C2)Br)/C#N

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

Characterization of radiation electrophysiological properties of U87 cells induced by ionizing radiation and STAT3 inhibitors under microelectrode matrix sensor

Publication Name: Brain Research Bulletin

Publication Date: 2025-09

DOI: 10.1016/j.brainresbull.2025.111448

Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways

Publication Name: Chemico-Biological Interactions

Publication Date: 2025-08-25

DOI: 10.1016/j.cbi.2025.111562

STAT3 inhibition in combination with CD47 blockade inhibits osteosarcoma lung metastasis

Publication Name: Frontiers in Immunology

Publication Date: 2025-06-03

DOI: 10.3389/fimmu.2025.1608375

A pH‐Sensitive Nanosized Covalent–Organic Polymer for Enhanced Tumor Photodynamic Immunotherapy by Hypoxia Relief and STAT3 Inhibition

Publication Name: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Publication Date: 2025-05-14

DOI: 10.1002/advs.202504860

WP1066, a small molecule inhibitor of STAT3, chemosensitizes paclitaxel-resistant ovarian cancer cells to paclitaxel by simultaneously inhibiting the activity of STAT3 and the interaction of STAT3 with Stathmin

Publication Name: Biochemical Pharmacology

Publication Date: 2024-03

DOI: 10.1016/j.bcp.2024.116040

WP1066, 98%, a novel inhibitor of JAK2 and STAT3

Product Information

General Information

Safety Information

References Data Source From Pubchem

Characterization of radiation electrophysiological properties of U87 cells induced by ionizing radiation and STAT3 inhibitors under microelectrode matrix sensor

Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways

STAT3 inhibition in combination with CD47 blockade inhibits osteosarcoma lung metastasis

A pH‐Sensitive Nanosized Covalent–Organic Polymer for Enhanced Tumor Photodynamic Immunotherapy by Hypoxia Relief and STAT3 Inhibition

WP1066, a small molecule inhibitor of STAT3, chemosensitizes paclitaxel-resistant ovarian cancer cells to paclitaxel by simultaneously inhibiting the activity of STAT3 and the interaction of STAT3 with Stathmin