SR17018, 98%

Name: SR17018, 98% | 2134602-45-0
Brand: J&K Chemical
SKU: JK9088511_5_MG
Price: 72.49 USD
Availability: OutOfStock

Cat. No JK9088511_5_MG

Vendor: J&K Chemical

Product Information

Product Name

SR17018, 98%

Brand Name

J&K

Product Number

9088511

CAS

2134602-45-0

Molecular Formula

C19H18Cl3N3O

Molecular Weight

410.72

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

130431397

IUPAC Name

5,6-dichloro-3-1-(4-chlorophenyl)methylpiperidin-4-yl-1H-benzimidazol-2-one

InChI Key

LAGUDYUGRSQDKS-UHFFFAOYSA-N

SMILES

C1CN(CCC1N2C3=CC(=C(C=C3NC2=O)Cl)Cl)CC4=CC=C(C=C4)Cl

Properties

Density

1.428

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

Molecular recognition of morphine and fentanyl by the human μ-opioid receptor

Publication Name: Cell

Publication Date: 2022-11-10

DOI: 10.1016/j.cell.2022.09.041

G protein signaling–biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists

Publication Name: Proceedings of the National Academy of Sciences of the United States of America

Publication Date: 2021-11-24

DOI: 10.1073/pnas.2102178118

Low Intrinsic Efficacy Alone Cannot Explain the Improved Side Effect Profiles of New Opioid Agonists

Publication Name: Biochemistry

Publication Date: 2021-09-01

DOI: 10.1021/acs.biochem.1c00466

SR-17018 Stimulates Atypical µ-Opioid Receptor Phosphorylation and Dephosphorylation

Publication Name: Molecules (Basel, Switzerland)

Publication Date: 2021-07-27

DOI: 10.3390/molecules26154509

Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain

Publication Name: Neuropharmacology

Publication Date: 2021-03-01

DOI: 10.1016/j.neuropharm.2020.108439

SR17018, 98%

Product Information

General Information

Properties

Safety Information

References Data Source From Pubchem

Molecular recognition of morphine and fentanyl by the human μ-opioid receptor

G protein signaling–biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists

Low Intrinsic Efficacy Alone Cannot Explain the Improved Side Effect Profiles of New Opioid Agonists

SR-17018 Stimulates Atypical µ-Opioid Receptor Phosphorylation and Dephosphorylation

Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain

SR17018, 98%

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-methoxy-L-phenylalanine

2-Ethynyl-1,3,5-trimethylbenzene, 97%

Tris-acetic acid electrophoresis buffer (50×TAE)

[S(R)]-N-[(1S)-1-[2-(Diadamantanphosphino)phenyl]ethyl]-N,2-dimethyl-2-propanesulfinamide, 95%

Mycophenolate Mofetil EP Impurity H

3-(4-Bromo-2-fluoro-3-methoxyphenyl)-3-oxo-propionic acid ethyl ester

Isochroman-1-carboxylic acid

Mycophenolate Mofetil

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SR17018, 98%

Product Information

General Information

Properties

Safety Information

References Data Source From Pubchem

Molecular recognition of morphine and fentanyl by the human μ-opioid receptor

G protein signaling–biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists

Low Intrinsic Efficacy Alone Cannot Explain the Improved Side Effect Profiles of New Opioid Agonists

SR-17018 Stimulates Atypical µ-Opioid Receptor Phosphorylation and Dephosphorylation

Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain

SR17018, 98%

Related Product

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-methoxy-L-phenylalanine

2-Ethynyl-1,3,5-trimethylbenzene, 97%

Tris-acetic acid electrophoresis buffer (50×TAE)

[S(R)]-N-[(1S)-1-[2-(Diadamantanphosphino)phenyl]ethyl]-N,2-dimethyl-2-propanesulfinamide, 95%

Mycophenolate Mofetil EP Impurity H

3-(4-Bromo-2-fluoro-3-methoxyphenyl)-3-oxo-propionic acid ethyl ester

Isochroman-1-carboxylic acid

Mycophenolate Mofetil

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