Product Introduction

2-Amino-2-methyl-1-propanol (AMP, CAS No. 124-68-5) is a multifunctional amino alcohol compound widely used as a biological buffer, pH regulator, neutralizing agent, and chemical intermediate.

With both primary amine (-NH₂) and hydroxyl (-OH) functional groups, AMP exhibits excellent buffering capability in the alkaline pH range and is commonly used in biochemistry, molecular biology, cosmetics, pharmaceutical formulations, coatings, and industrial chemistry.

AMP is particularly valuable as an alternative buffering reagent to traditional amines because of its high water solubility, low volatility compared with ammonia-based systems, and compatibility with biological and chemical formulations.

Structural Characteristics

Amino Group (-NH₂)

The amino group provides:

• Proton acceptance ability
• pH adjustment capability
• Buffering function
• Chemical reactivity

Hydroxyl Group (-OH)

The hydroxyl group contributes:

• Water solubility
• Hydrogen bonding ability
• Compatibility with aqueous formulations
• Improved formulation stability

Branched Carbon Structure

The branched molecular structure provides:

• Low steric interference
• Good chemical stability
• Reduced volatility compared with smaller amines

Key Research Applications

1. Biological Buffer Systems

AMP is used as a buffering reagent in biochemical research.

Applications include:

• Enzyme assays
• Protein studies
• Biological sample preparation
• Cell-related research
• Biochemical reaction optimization

Its buffering range makes it suitable for maintaining alkaline pH conditions.

2. Pharmaceutical and Biomedical Formulations

AMP is used as a pH-adjusting and stabilizing component.

Applications include:

• Pharmaceutical formulation development
• Buffer systems
• Drug delivery studies
• Topical formulations
• Biomedical material research

3. Cosmetics and Personal Care Products

AMP is widely used in cosmetic formulations.

Applications include:

• pH adjustment
• Emulsion stabilization
• Hair care products
• Skin care formulations
• Personal care ingredient systems

It helps maintain formulation stability and product performance.

4. Industrial Coatings and Paints

AMP is an important additive in coating technologies.

Applications include:

• Water-based coatings
• Paint formulations
• Latex systems
• Surface treatment materials
• Polymer dispersions

It improves pH control and formulation stability.

5. Gas Treatment and CO₂ Capture Research

Amino alcohols are investigated in gas absorption systems.

Applications include:

• Carbon dioxide capture research
• Gas purification studies
• Absorbent formulation development
• Environmental technology research

The amino group enables reversible interaction with acidic gases.

6. Chemical Synthesis Intermediate

AMP serves as a building block in organic synthesis.

Applications include:

• Pharmaceutical intermediates
• Functional amine synthesis
• Organic modification reactions
• Specialty chemical preparation

Advantages

• Effective alkaline buffering capacity
• High water solubility
• Multifunctional amino alcohol structure
• Good chemical stability
• Suitable for biological and industrial applications
• Low odor compared with some volatile amines

Storage & Handling

• Store in a cool place.
• Keep container tightly closed in a dry and well-ventilated place.
• Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Research Areas

• Biochemistry
• Molecular biology
• Pharmaceutical formulation
• Cosmetics chemistry
• Polymer science
• Environmental chemistry
• Industrial formulation technology

Q1: What is 2-Amino-2-methyl-1-propanol?

A: 2-Amino-2-methyl-1-propanol (AMP, CAS No. 124-68-5) is an amino alcohol compound used as a buffer, pH regulator, and chemical intermediate.

Q2: What is AMP used for?

A: AMP is mainly used in:

• Biological buffer systems
• Pharmaceutical formulations
• Cosmetics
• Coatings
• Chemical synthesis
• Gas treatment research

Q3: Is AMP a biological buffer?

A: Yes. AMP can function as an alkaline buffer and is used in biochemical research where stable pH control is required.

Q4: What is the difference between AMP and Tris buffer?

Q5: Can AMP be used in protein research?

A: Yes. AMP can be used as a buffering component in enzyme assays and protein-related biochemical studies.

Q6: Why is AMP used in cosmetics?

A: AMP provides pH adjustment and formulation stabilization properties, making it useful in creams, lotions, and hair-care products.

Q7: Is AMP used in CO₂ capture research?

A: Yes. Amino alcohol compounds such as AMP are studied as CO₂ absorbents because amine groups can interact with acidic gases.

Q8: How should AMP be stored?

A: Store AMP in a tightly sealed container at room temperature under dry conditions and avoid contamination.