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Barasertib-HQPA, 99%, a highly selective Aurora B inhibitor|804158|722544-51-6

Barasertib-HQPA, 99%, a highly selective Aurora B inhibitor

Cat. No JK804158_5_MG
J&K Chemical

Product Information

Product Name
Barasertib-HQPA, 99%, a highly selective Aurora B inhibitor
Brand Name
J&K
Product Number
804158
CAS
722544-51-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
16007391
IUPAC Name
2-3-7-3-ethyl(2-hydroxyethyl)aminopropoxyquinazolin-4-ylamino-1H-pyrazol-5-yl-N-(3-fluorophenyl)acetamide
InChI Key
QYZOGCMHVIGURT-UHFFFAOYSA-N
SMILES
CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO

Safety Information

Storage Condition
Freezer -20℃

References Data Source From Pubchem

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma
Publication Name: Cancer Letters
Publication Date: 2023-08-01
DOI: 10.1016/j.canlet.2023.216284

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer
Publication Name: Science Translational Medicine
Publication Date: 2023-06-21
DOI: 10.1126/scitranslmed.add7872

Targeting BCL2 Overcomes Resistance and Augments Response to Aurora Kinase B Inhibition by AZD2811 in Small Cell Lung Cancer
Publication Name: Clinical cancer research : an official journal of the American Association for Cancer Research
Publication Date: 2023-06-08
DOI: 10.1158/1078-0432.ccr-23-0375

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma
Publication Name: Journal of experimental & clinical cancer research : CR
Publication Date: 2023-04-25
DOI: 10.1186/s13046-023-02667-4

Target Class Profiling of Small-Molecule Methyltransferases
Publication Name: ACS Chemical Biology
Publication Date: 2023-03-28
DOI: 10.1021/acschembio.3c00124

Barasertib-HQPA, 99%, a highly selective Aurora B inhibitor

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