RG108, 98%, a non-nucleoside inhibitor of DNA methyltransferase with an IC50 of 115 Nm

Name: RG108, 98%, a non-nucleoside inhibitor of DNA methyltransferase with an IC50 of 115 Nm | 48208-26-0
Brand: J&K Chemical
SKU: JK688347_10_MG
Price: 64.8 USD
Availability: OutOfStock

Cat. No JK688347_10_MG

Vendor: J&K Chemical

Product Information

Product Name

RG108, 98%, a non-nucleoside inhibitor of DNA methyltransferase with an IC50 of 115 Nm

Brand Name

J&K

Product Number

688347

CAS

48208-26-0

SDS Document

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Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

344265

IUPAC Name

2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid

InChI Key

HPTXLHAHLXOAKV-UHFFFAOYSA-N

SMILES

C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

DNA 5mC methylation inhibits the formation of G-quadruplex structures in the genome

Publication Name: Genome Biology

Publication Date: 2025-07-11

DOI: 10.1186/s13059-025-03678-4

Recent advances on gene-related DNA methylation in cancer diagnosis, prognosis, and treatment: a clinical perspective

Publication Name: Clinical Epigenetics

Publication Date: 2025-05-05

DOI: 10.1186/s13148-025-01884-2

Epigenetic marvels: exploring the landscape of colorectal cancer treatment through cutting-edge epigenetic-based drug strategies

Publication Name: Clinical Epigenetics

Publication Date: 2025-02-22

DOI: 10.1186/s13148-025-01844-w

RG108 attenuates acute kidney injury by inhibiting P38 MAPK/FOS and JNK/JUN pathways

Publication Name: International Immunopharmacology

Publication Date: 2024-12-05

DOI: 10.1016/j.intimp.2024.113077

Enhancing antitumor activity of herceptin in HER2-positive breast cancer cells: a novel DNMT-1 inhibitor approach

Publication Name: Discover Oncology

Publication Date: 2024-11-11

DOI: 10.1007/s12672-024-01508-w

RG108, 98%, a non-nucleoside inhibitor of DNA methyltransferase with an IC50 of 115 Nm

Product Information

General Information

Safety Information

References Data Source From Pubchem

DNA 5mC methylation inhibits the formation of G-quadruplex structures in the genome

Recent advances on gene-related DNA methylation in cancer diagnosis, prognosis, and treatment: a clinical perspective

Epigenetic marvels: exploring the landscape of colorectal cancer treatment through cutting-edge epigenetic-based drug strategies

RG108 attenuates acute kidney injury by inhibiting P38 MAPK/FOS and JNK/JUN pathways

Enhancing antitumor activity of herceptin in HER2-positive breast cancer cells: a novel DNMT-1 inhibitor approach