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AG-1478, 97.5%, a selective EGFR inhibitor|384719|153436-53-4

AG-1478, 97.5%, a selective EGFR inhibitor

Cat. No JK384719_5_MG
J&K Chemical

Product Information

Product Name
AG-1478, 97.5%, a selective EGFR inhibitor
Brand Name
J&K
Product Number
384719
CAS
153436-53-4
SDS Document
View/Download
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2051
IUPAC Name
N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
InChI Key
GFNNBHLJANVSQV-UHFFFAOYSA-N
SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC

Safety Information

Storage Condition
Freezer -20℃

References Data Source From Pubchem

Large scale compound selection guided by cell painting reveals activity cliffs and functional relationships
Publication Name: Communications Biology
Publication Date: 2026-01-13
DOI: 10.1038/s42003-025-09500-y

The mechanism of S100A8/A9 heterodimer promoting atherosclerotic thrombosis
Publication Name: Clinical and Experimental Medicine
Publication Date: 2025-12-31
DOI: 10.1007/s10238-025-02016-z

Early-phase impact of obesity-associated stress on murine vascular smooth muscle cells depends on EGFR and sex
Publication Name: Communications Biology
Publication Date: 2025-12-22
DOI: 10.1038/s42003-025-09416-7

GABA treatment promoting cell apoptosis in meningioma correlates with EGFR/BCL-2/BAX axis
Publication Name: Journal of Neuro-Oncology
Publication Date: 2025-11-11
DOI: 10.1007/s11060-025-05334-0

Advances in sweat gland organoids: construction, molecular mechanisms, and challenges
Publication Name: Stem Cell Research & Therapy
Publication Date: 2025-10-28
DOI: 10.1186/s13287-025-04689-5

AG-1478, 97.5%, a selective EGFR inhibitor

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