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Sunitinib, 98%, a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively|381939|557795-19-4

Sunitinib, 98%, a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively

Cat. No JK381939_50_MG
J&K Chemical

Product Information

Product Name
Sunitinib, 98%, a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively
Brand Name
J&K
Product Number
381939
CAS
557795-19-4
Molecular Formula
C22H27FN4O2
Molecular Weight
398.47
SDS Document
View/Download
Certificate of Analysis (COA)​
COA not found

General Information

Synonyms
  • Sutent
  • sunitinibum
PubChem CID
5329102
IUPAC Name
N-2-(diethylamino)ethyl-5-(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl-2,4-dimethyl-1H-pyrrole-3-carboxamide
InChI Key
WINHZLLDWRZWRT-ATVHPVEESA-N
SMILES
CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\2/C3=C(C=CC(=C3)F)NC2=O)C

Properties

Density
1.2
Melting Point
234-246
Boiling Point
572.1
Flash Point
299.8
n20D
1.6100

Safety Information

Precautionary Statement
P262
Storage Condition
Freezer -20℃

References Data Source From Pubchem

Pattern of disease recurrence and outcomes after progression of high-risk renal cell carcinoma (RCC) patients treated with adjuvant immunotherapy
Publication Name: Cancer immunology, immunotherapy : CII
Publication Date: 2026-02-25
DOI: 10.1007/s00262-026-04331-0

A real-world comparison of nivolumab plus cabozantinib and pembrolizumab plus lenvatinib focusing on safety outcomes in metastatic renal cell carcinoma: results from the JK-FOOT consortium
Publication Name: Cancer immunology, immunotherapy : CII
Publication Date: 2026-02-25
DOI: 10.1007/s00262-025-04288-6

Safety profile of FLT3 inhibitors in acute myeloid leukemia: a systematic review and meta-analysis of adverse events
Publication Name: Clinical and Experimental Medicine
Publication Date: 2026-02-23
DOI: 10.1007/s10238-026-02093-8

Clinical utility of the ESTRO–EORTC classification in oligometastatic disease treated with stereotactic body radiotherapy: a single-institution retrospective study
Publication Name: Clinical & Experimental Metastasis
Publication Date: 2026-02-20
DOI: 10.1007/s10585-026-10398-x

The pancreatic cancer drug market
Publication Name: Nature reviews. Drug discovery
Publication Date: 2026-02-20
DOI: 10.1038/d41573-026-00027-3

Sunitinib, 98%, a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively

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