Mitoxantrone hydrochloride, 98%, a topoisomerase II inhibitor; also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM

Name: Mitoxantrone hydrochloride, 98%, a topoisomerase II inhibitor; also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM | 70476-82-3
Brand: J&K Chemical
SKU: JK289285_1_G
Price: 456.0 USD
Availability: OutOfStock

Cat. No JK289285_1_G

Vendor: J&K Chemical

Product Information

Product Name

Mitoxantrone hydrochloride, 98%, a topoisomerase II inhibitor; also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM

Brand Name

J&K

Product Number

289285

CAS

70476-82-3

Molecular Formula

C22H28N4O6·2HCl

Molecular Weight

517.40

SDS Document

View/Download

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

51082

IUPAC Name

1,4-dihydroxy-5,8-bis2-(2-hydroxyethylamino)ethylaminoanthracene-9,10-dione;dihydrochloride

InChI Key

ZAHQPTJLOCWVPG-UHFFFAOYSA-N

SMILES

C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

Synergistic innovations of nanomedicine in lymphoma treatment: a systematic review

Publication Name: Journal of Translational Medicine

Publication Date: 2025-12-09

DOI: 10.1186/s12967-025-07249-w

The Rac1-USP11 feedback amplification loop: a radiation-activated engine driving radioresistance in hepatocellular carcinoma

Publication Name: British Journal of Cancer

Publication Date: 2025-11-26

DOI: 10.1038/s41416-025-03265-1

Targeting triple-negative breast cancer: apoptotic and antitumor effects of Artemisia sieberi Besser extracts

Publication Name: Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Publication Date: 2025-11-24

DOI: 10.1007/s44446-025-00047-x

Design and Evaluation of π-π Stacking-driven Polymeric Nanoparticles for Co-delivery of siRNA and Irinotecan

Publication Name: Journal of Pharmaceutical Innovation

Publication Date: 2025-10-31

DOI: 10.1007/s12247-025-10167-5

Multiple drugs

Publication Name: Reactions Weekly

Publication Date: 2025-08-02

DOI: 10.1007/s40278-025-87412-5

Mitoxantrone hydrochloride, 98%, a topoisomerase II inhibitor; also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM

Product Information

General Information

Safety Information

References Data Source From Pubchem

Synergistic innovations of nanomedicine in lymphoma treatment: a systematic review

The Rac1-USP11 feedback amplification loop: a radiation-activated engine driving radioresistance in hepatocellular carcinoma

Targeting triple-negative breast cancer: apoptotic and antitumor effects of Artemisia sieberi Besser extracts

Design and Evaluation of π-π Stacking-driven Polymeric Nanoparticles for Co-delivery of siRNA and Irinotecan

Multiple drugs