Toosendanin, 98%, from Melia toosendan Sieb. et Zucc.

Name: Toosendanin, 98%, from Melia toosendan Sieb. et Zucc. | 58812-37-6
Brand: J&K Chemical
SKU: JK212800_5_MG
Price: 207.0 USD
Availability: OutOfStock

Cat. No JK212800_5_MG

Vendor: J&K Chemical

Product Information

Product Name

Toosendanin, 98%, from Melia toosendan Sieb. et Zucc.

Brand Name

J&K

Product Number

212800

CAS

58812-37-6

Molecular Formula

C30H38O11

Molecular Weight

574.62

SDS Document

View/Download

Certificate of Analysis (COA)

COA not found

General Information

Synonyms

14,15-Epoxy-4,10-(methanoxymethano)-1H-cyclopentaaphenanthrene
24-Norchola-20,22-diene-4-carboxaldehyde Deriv
28-Deacetylsendanin
Chuanliansu

PubChem CID

9851101

IUPAC Name

(1S,2R,4R,5R,6S,8R,10S,11S,12R,14R,15R,16R,19S,21R)-4-acetyloxy-6-(furan-3-yl)-12,16,19-trihydroxy-5,11,15-trimethyl-3-oxo-9,17-dioxahexacyclo13.3.3.01,14.02,11.05,10.08,10henicosan-21-yl acetate

InChI Key

NAHTXVIXCMUDLF-RFNFAWMESA-N

SMILES

CC(=O)OC@@H1CC@@H(C@@23COC@H(C@@1(C@@H2CC@H(C@@4(C@@H3C(=O)C@@H(C@@5(C@46C@H(O6)CC@H5C7=COC=C7)C)OC(=O)C)C)O)C)O)O

Properties

Melting Point

170-175

Safety Information

Precautionary Statement

P262

Storage Condition

Store at 2-8℃

References Data Source From Pubchem

Site-selective structural modification of toosendanin enables one-step synthesis of 12-hydroxyamoorastatin: A natural tautomeric antitumor lead with low toxicity

Publication Name: Bioorganic Chemistry

Publication Date: 2025-07-01

DOI: 10.1016/j.bioorg.2025.108578

Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade

Publication Name: Phytomedicine : international journal of phytotherapy and phytopharmacology

Publication Date: 2025-05

DOI: 10.1016/j.phymed.2025.156586

Toosendanin Induces Cell Cycle Arrest and Apoptosis to Suppress Diffuse Large B‐Cell Lymphoma Growth by Inhibiting PI3Kα/β and PLK1 Signaling

Publication Name: Phytotherapy research : PTR

Publication Date: 2025-02-13

DOI: 10.1002/ptr.8439

Toosendanin alleviates acute lung injury by reducing pulmonary vascular barrier dysfunction mediated by endoplasmic reticulum stress through mTOR

Publication Name: Phytomedicine : international journal of phytotherapy and phytopharmacology

Publication Date: 2025-01

DOI: 10.1016/j.phymed.2024.156277

Toosendanin: upgrade of an old agent in cancer treatment

Publication Name: Chinese Journal of Natural Medicines

Publication Date: 2024-10

DOI: 10.1016/s1875-5364(24)60693-x

Toosendanin, 98%, from Melia toosendan Sieb. et Zucc.

Product Information

General Information

Properties

Safety Information

References Data Source From Pubchem

Site-selective structural modification of toosendanin enables one-step synthesis of 12-hydroxyamoorastatin: A natural tautomeric antitumor lead with low toxicity

Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade

Toosendanin Induces Cell Cycle Arrest and Apoptosis to Suppress Diffuse Large B‐Cell Lymphoma Growth by Inhibiting PI3Kα/β and PLK1 Signaling

Toosendanin alleviates acute lung injury by reducing pulmonary vascular barrier dysfunction mediated by endoplasmic reticulum stress through mTOR

Toosendanin: upgrade of an old agent in cancer treatment