PFI-4, 98%, a potent and selective and cell permeable BRPF1 bromodomain inhibitor

Name: PFI-4, 98%, a potent and selective and cell permeable BRPF1 bromodomain inhibitor | 900305-37-5
Brand: J&K Chemical
SKU: JK2062538_5_MG
Price: 60.8 USD
Availability: OutOfStock

Cat. No JK2062538_5_MG

Vendor: J&K Chemical

Product Information

Product Name

PFI-4, 98%, a potent and selective and cell permeable BRPF1 bromodomain inhibitor

Brand Name

J&K

Product Number

2062538

CAS

900305-37-5

SDS Document

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Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

40642506

IUPAC Name

N-(1,3-dimethyl-2-oxo-6-pyrrolidin-1-ylbenzimidazol-5-yl)-2-methoxybenzamide

InChI Key

QCIJLRJBZDBVDB-UHFFFAOYSA-N

SMILES

CN1C2=C(C=C(C(=C2)NC(=O)C3=CC=CC=C3OC)N4CCCC4)N(C1=O)C

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

Development of 3-acetylindole derivatives that selectively target BRPF1 as new inhibitors of receptor activator of NF-κB ligand (RANKL)-Induced osteoclastogenesis

Publication Name: Bioorganic & Medicinal Chemistry

Publication Date: 2023-12-15

DOI: 10.1016/j.bmc.2023.117440

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer

Publication Name: Science Translational Medicine

Publication Date: 2023-06-21

DOI: 10.1126/scitranslmed.add7872

Target Class Profiling of Small-Molecule Methyltransferases

Publication Name: ACS Chemical Biology

Publication Date: 2023-03-28

DOI: 10.1021/acschembio.3c00124

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

Publication Name: Proceedings of the National Academy of Sciences of the United States of America

Publication Date: 2020-11-23

DOI: 10.1073/pnas.2005463117

High-Throughput Screening to Identify Inhibitors of the Type I Interferon–Major Histocompatibility Complex Class I Pathway in Skeletal Muscle

Publication Name: ACS Chemical Biology

Publication Date: 2020-05-27

DOI: 10.1021/acschembio.0c00343

PFI-4, 98%, a potent and selective and cell permeable BRPF1 bromodomain inhibitor

Product Information

General Information

Safety Information

References Data Source From Pubchem

Development of 3-acetylindole derivatives that selectively target BRPF1 as new inhibitors of receptor activator of NF-κB ligand (RANKL)-Induced osteoclastogenesis

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer

Target Class Profiling of Small-Molecule Methyltransferases

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

High-Throughput Screening to Identify Inhibitors of the Type I Interferon–Major Histocompatibility Complex Class I Pathway in Skeletal Muscle