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SGI-1027, 98%, a DNA methyltransferase (DNMT) inhibitor|1834612|1020149-73-8

SGI-1027, 98%, a DNA methyltransferase (DNMT) inhibitor

Cat. No JK1834612_50_MG
J&K Chemical

Product Information

Product Name
SGI-1027, 98%, a DNA methyltransferase (DNMT) inhibitor
Brand Name
J&K
Product Number
1834612
CAS
1020149-73-8
SDS Document
View/Download
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
24858111
IUPAC Name
N-4-(2-amino-6-methylpyrimidin-4-yl)aminophenyl-4-(quinolin-4-ylamino)benzamide
InChI Key
QSYLKMKIVWJAAK-UHFFFAOYSA-N
SMILES
CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)NC4=CC=NC5=CC=CC=C54

Safety Information

Storage Condition
Freezer -20℃

References Data Source From Pubchem

Target Class Profiling of Small-Molecule Methyltransferases
Publication Name: ACS Chemical Biology
Publication Date: 2023-03-28
DOI: 10.1021/acschembio.3c00124

Discovery of novel non-nucleoside inhibitors with high potency and selectivity for DNA methyltransferase 3A
Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2022-11-15
DOI: 10.1016/j.ejmech.2022.114646

Recent contributions of quinolines to antimalarial and anticancer drug discovery research
Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2021-12-15
DOI: 10.1016/j.ejmech.2021.113865

Cyclophosphamide inhibits Pax5 methylation to regulate the growth of retinoblastoma via the Notch1 pathway
Publication Name: Human & Experimental Toxicology
Publication Date: 2021-10-18
DOI: 10.1177/09603271211051601

Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer
Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2021-09-01
DOI: 10.1016/j.bmc.2021.116324

SGI-1027, 98%, a DNA methyltransferase (DNMT) inhibitor

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