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SB 203580, 98%, a selective and ATP-competitive p38 MAPK inhibitor|176239|152121-47-6

SB 203580, 98%, a selective and ATP-competitive p38 MAPK inhibitor

Cat. No JK176239_500_MG
J&K Chemical

Product Information

Product Name
SB 203580, 98%, a selective and ATP-competitive p38 MAPK inhibitor
Brand Name
J&K
Product Number
176239
CAS
152121-47-6
Molecular Formula
C21H16FN3OS
Molecular Weight
377.43
SDS Document
View/Download
Certificate of Analysis (COA)​
COA not found

General Information

Synonyms
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole
PubChem CID
176155
IUPAC Name
4-4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-ylpyridine
InChI Key
CDMGBJANTYXAIV-UHFFFAOYSA-N
SMILES
CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F

Properties

Density
1.4
Melting Point
168-175
Boiling Point
615.6
n20D
1.71

Safety Information

GHS Symbols
Hazard Symbol
Hazard Symbol
Signal Word
Danger
Hazard Statement
H302
H318
Precautionary Statement
P270
P330
P501
P280
P301+P317
P264+P265
P305+P354+P338
Storage Condition
Freezer -20℃

References Data Source From Pubchem

Correction: Aspirin alleviates cardiac fibrosis in mice by inhibiting autophagy
Publication Name: Acta Pharmacologica Sinica
Publication Date: 2026-03-04
DOI: 10.1038/s41401-026-01780-2

Nicotinamide mononucleotide and nicotinamide riboside attenuate cytokine production in human keratinocytes via suppression of p38 Pathway
Publication Name: Molecular Biology Reports
Publication Date: 2026-03-04
DOI: 10.1007/s11033-026-11615-2

Enhancing KLF15 activity in cardiomyocytes: a novel approach to prevent pathological reprogramming and fibrosis via nuclease-deficient dCas9VPR
Publication Name: Signal Transduction and Targeted Therapy
Publication Date: 2026-03-03
DOI: 10.1038/s41392-026-02593-9

Integrator subunit INTS12 links ribotoxic stress to transcription-coupled nucleotide excision repair
Publication Name: Nature Structural & Molecular Biology
Publication Date: 2026-02-26
DOI: 10.1038/s41594-026-01766-y

CNOT9 affects hepatocellular carcinoma proliferation and cell cycle through the PTEN/AKT/p53 signaling pathway
Publication Name: Human Cell
Publication Date: 2026-02-25
DOI: 10.1007/s13577-026-01349-5|10.1007/s13577-026-01406-z

SB 203580, 98%, a selective and ATP-competitive p38 MAPK inhibitor

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