AZD1480, 98%, a novel ATP-competitive JAK2 inhibitor

Name: AZD1480, 98%, a novel ATP-competitive JAK2 inhibitor | 935666-88-9
Brand: J&K Chemical
SKU: JK1758453_100_MG
Price: 954.0 USD
Availability: OutOfStock

Cat. No JK1758453_100_MG

Vendor: J&K Chemical

Product Information

Product Name

AZD1480, 98%, a novel ATP-competitive JAK2 inhibitor

Brand Name

J&K

Product Number

1758453

CAS

935666-88-9

SDS Document

View/Download

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

16659841

IUPAC Name

5-chloro-2-N-(1S)-1-(5-fluoropyrimidin-2-yl)ethyl-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

InChI Key

PDOQBOJDRPLBQU-QMMMGPOBSA-N

SMILES

CC1=CC(=NN1)NC2=NC(=NC=C2Cl)NC@@H(C)C3=NC=C(C=N3)F

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors

Publication Name: Bioorganic & Medicinal Chemistry

Publication Date: 2024-01-15

DOI: 10.1016/j.bmc.2023.117561

TTD: Therapeutic Target Database describing target druggability information

Publication Name: Nucleic Acids Research

Publication Date: 2023-09-15

DOI: 10.1093/nar/gkad751

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

Publication Name: Cancer Letters

Publication Date: 2023-08-01

DOI: 10.1016/j.canlet.2023.216284

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer

Publication Name: Science Translational Medicine

Publication Date: 2023-06-21

DOI: 10.1126/scitranslmed.add7872

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma

Publication Name: Journal of experimental & clinical cancer research : CR

Publication Date: 2023-04-25

DOI: 10.1186/s13046-023-02667-4

AZD1480, 98%, a novel ATP-competitive JAK2 inhibitor

Product Information

General Information

Safety Information

References Data Source From Pubchem

Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors

TTD: Therapeutic Target Database describing target druggability information

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma