Cat. No JK1684920_25_MG
J&K Chemical

Product Information

Product Name
Rociletinib, 98%, an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.
Brand Name
J&K
Product Number
1684920
CAS
1374640-70-6
Molecular Formula
C27H28F3N7O3
Molecular Weight
555.55
SDS Document
Certificate of Analysis (COA)​
COA not found

General Information

Synonyms
  • CO-1686
  • AVL-301
PubChem CID
57335384
IUPAC Name
N-3-2-4-(4-acetylpiperazin-1-yl)-2-methoxyanilino-5-(trifluoromethyl)pyrimidin-4-ylaminophenylprop-2-enamide
InChI Key
HUFOZJXAKZVRNJ-UHFFFAOYSA-N
SMILES
CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OC

Safety Information

GHS Symbols
Hazard Symbol
Signal Word
Warning
Hazard Statement
H315
H320
Precautionary Statement
P280
P321
P302+P352
P332+P317
P362+P364
P264+P265
P305+P351+P338
P337+P317
Storage Condition
Freezer -20℃

Rociletinib, 98%, an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.

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