PD153035 Hydrochloride, 98%, a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively.

Name: PD153035 Hydrochloride, 98%, a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively. | 183322-45-4
Brand: J&K Chemical
SKU: JK1548518_10_MG
Price: 74.1 USD
Availability: OutOfStock

Cat. No JK1548518_10_MG

Vendor: J&K Chemical

Product Information

Product Name

PD153035 Hydrochloride, 98%, a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively.

Brand Name

J&K

Product Number

1548518

CAS

183322-45-4

SDS Document

View/Download

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

11246488

IUPAC Name

N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride

InChI Key

ZJOKWAWPAPMNIM-UHFFFAOYSA-N

SMILES

COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

DMP-1 promoter-associated antisense strand non-coding RNA, panRNA-DMP-1, physically associates with EGFR to repress EGF-induced squamous cell carcinoma migration

Publication Name: Molecular and Cellular Biochemistry

Publication Date: 2021-01-09

DOI: 10.1007/s11010-020-04046-5

Reduced annexin A6 expression promotes the degradation of activated epidermal growth factor receptor and sensitizes invasive breast cancer cells to EGFR-targeted tyrosine kinase inhibitors

Publication Name: Molecular Cancer

Publication Date: 2013-12-19

DOI: 10.1186/1476-4598-12-167

Anilinodialkoxyquinazolines: Screening Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Potential Tumor Imaging Probes

Publication Name: Journal of Medicinal Chemistry

Publication Date: 2005-10-20

DOI: 10.1021/jm050607w

PD153035 Hydrochloride, 98%, a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively.

Product Information

General Information

Safety Information

References Data Source From Pubchem

DMP-1 promoter-associated antisense strand non-coding RNA, panRNA-DMP-1, physically associates with EGFR to repress EGF-induced squamous cell carcinoma migration

Reduced annexin A6 expression promotes the degradation of activated epidermal growth factor receptor and sensitizes invasive breast cancer cells to EGFR-targeted tyrosine kinase inhibitors

Anilinodialkoxyquinazolines: Screening Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Potential Tumor Imaging Probes