PF-573228, 98%, a potent and selective FAK inhibitor

Name: PF-573228, 98%, a potent and selective FAK inhibitor | 869288-64-2
Brand: J&K Chemical
SKU: JK1433442_10_MG
Price: 115.9 USD
Availability: InStock

Cat. No JK1433442_10_MG

Vendor: J&K Chemical

Product Information

Product Name

PF-573228, 98%, a potent and selective FAK inhibitor

Brand Name

J&K

Product Number

1433442

CAS

869288-64-2

SDS Document

View/Download

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

11612883

IUPAC Name

6-4-(3-methylsulfonylphenyl)methylamino-5-(trifluoromethyl)pyrimidin-2-ylamino-3,4-dihydro-1H-quinolin-2-one

InChI Key

HESLKTSGTIBHJU-UHFFFAOYSA-N

SMILES

CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4

Safety Information

Storage Condition

Freezer -20℃

References Data Source From Pubchem

Loss of MTA2‐mediated downregulation of PTK7 inhibits hepatocellular carcinoma metastasis progression by modulating the FAK‐MMP7 axis

Publication Name: Environmental Toxicology

Publication Date: 2023-12-05

DOI: 10.1002/tox.24073

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

Publication Name: Cancer Letters

Publication Date: 2023-08-01

DOI: 10.1016/j.canlet.2023.216284

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer

Publication Name: Science Translational Medicine

Publication Date: 2023-06-21

DOI: 10.1126/scitranslmed.add7872

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma

Publication Name: Journal of experimental & clinical cancer research : CR

Publication Date: 2023-04-25

DOI: 10.1186/s13046-023-02667-4

Target Class Profiling of Small-Molecule Methyltransferases

Publication Name: ACS Chemical Biology

Publication Date: 2023-03-28

DOI: 10.1021/acschembio.3c00124

PF-573228, 98%, a potent and selective FAK inhibitor

Product Information

General Information

Safety Information

References Data Source From Pubchem

Loss of MTA2‐mediated downregulation of PTK7 inhibits hepatocellular carcinoma metastasis progression by modulating the FAK‐MMP7 axis

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA -mutant ovarian cancer

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma

Target Class Profiling of Small-Molecule Methyltransferases