Product Name
Levistilide A, 98%, from Angelica sinensis (Oliv.) Diels
Molecular Formula
C24H28O4
Certificate of Analysis (COA)
Product Introduction
Levistilide A is a naturally occurring phthalide dimer compound isolated from traditional medicinal plants such as Ligusticum chuanxiong and Angelica sinensis. It belongs to the class of bioactive natural products widely studied in pharmacology, oncology, neuroprotection, and natural medicine research.
Levistilide A has attracted increasing research interest due to its reported activities involving oxidative stress regulation, apoptosis modulation, inflammation-associated pathways, and cellular signaling mechanisms. Studies have investigated its role in ROS-mediated cellular responses, cancer biology, and natural product pharmacology research.
Due to its distinctive dimeric phthalide structure and biological relevance, Levistilide A is widely used in natural product studies, mechanism-of-action research, and bioactive compound screening.
Chemical Properties and Reaction Mechanism
Levistilide A functions as a bioactive natural small molecule used primarily in pharmacological and biochemical research.
In biological systems, reported research suggests involvement in:
- Regulation of reactive oxygen species (ROS)-related pathways
- Modulation of cellular apoptosis and stress responses
- Investigation of signal transduction and bioactive natural product mechanisms
Key characteristics include:
- Phthalide dimer natural product structure
- Lipophilic organic framework
- Suitable for cellular and molecular biology research applications
Its unique structure makes it valuable for mechanistic studies and natural compound activity evaluation.
Key Research Applications
1.Natural Product Research
Levistilide A is widely used in natural product and phytochemical studies.
Typical applications include:
- Natural compound isolation studies
- Botanical constituent analysis
- Structure–activity relationship research
2.Cancer and Cell Biology Research
The compound is frequently investigated in cellular response and oncology-related studies.
Applications include:
- Apoptosis pathway research
- ROS-associated cellular studies
- Tumor biology investigations
3.Pharmacological Mechanism Studies
Useful in mechanism-of-action research.
Applications include:
- Cellular signaling pathway studies
- Bioactive small molecule evaluation
- Molecular pharmacology investigations
4.Traditional Medicine and Bioactive Compound Research
Widely applied in traditional medicine-derived compound studies.
Applications include:
- Herbal bioactive constituent analysis
- Natural medicine research
- Functional compound screening
Recommended Experimental Conditions
| Parameter |
Recommended Conditions |
| Application Type |
Natural product / pharmacology research |
| Solvent Systems |
DMSO, ethanol, methanol, or compatible organic solvents |
| Experimental Models |
Cell-based assays, biochemical assays |
| Temperature |
Application-dependent |
| Assay Format |
Molecular biology, pharmacology, analytical workflows |
Experimental conditions should be optimized according to assay design and biological model requirements.
Advantages in Research Applications
- Bioactive natural phthalide compound
- Relevant to oxidative stress and cellular signaling research
- Suitable for natural product and pharmacology studies
- Compatible with molecular and cellular assay systems
- Valuable for mechanism-of-action investigations
Storage & Handling
Store in a cool place. Keep container tightly closed in a dry and well ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Research Areas
Researchers working in the following fields may benefit from this compound:
- Natural products and phytochemistry research
- Pharmacology and molecular biology
- Cancer and apoptosis research
- Oxidative stress and signaling pathway studies
- Traditional medicine bioactive compound research
Frequently Asked Questions (FAQ)
What is Levistilide A used for?
It is widely used in natural product, pharmacology, and cell biology research.
What type of compound is Levistilide A?
Levistilide A is a natural phthalide dimer compound isolated from medicinal plants including Ligusticum and Angelica species.
Is Levistilide A used in cancer research?
Yes, it has been investigated in studies involving apoptosis, ROS signaling, and cancer-related cellular mechanisms.
Which experimental systems are commonly used with Levistilide A?
Typical systems include cell culture assays, molecular biology experiments, and pharmacological screening workflows.
What solvents are commonly used for Levistilide A preparation?
Researchers frequently use DMSO or compatible organic solvents, depending on experimental requirements.
Does assay optimization matter when using Levistilide A?
Yes, factors such as concentration, solvent system, biological model, and incubation conditions should be optimized experimentally.