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Chem Impex
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Product Information

Product Name
5-Iodouridine
Brand Name
Chem Impex
Product Number
00807
CAS
1024-99-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
1268108
IUPAC Name
1-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl-5-iodopyrimidine-2,4-dione
InChI Key
RKSLVDIXBGWPIS-UAKXSSHOSA-N
SMILES
C1=C(C(=O)NC(=O)N1C@H2C@@H(C@@H(C@H(O2)CO)O)O)I

Application

5-Iodouridine is widely utilized in research focused on:

Antiviral Research: It serves as a key compound in developing antiviral therapies, particularly against viruses like herpes simplex virus (HSV) and cytomegalovirus (CMV), providing a basis for new treatment options.

Nucleoside Analog Studies: This compound is crucial in studying nucleoside analogs, which can help researchers understand mechanisms of action and resistance in viral infections, aiding in drug design.

Biochemical Assays: 5-Iodouridine is used in various biochemical assays to investigate nucleic acid metabolism, allowing scientists to explore cellular processes and potential therapeutic targets.

Pharmaceutical Development: It plays a role in the synthesis of new pharmaceuticals, particularly in the field of oncology, where it can be used to develop targeted therapies that interfere with tumor growth.

Diagnostic Applications: The compound can be utilized in diagnostic tests for viral infections, enhancing the accuracy of detection methods and improving patient outcomes.

References Data Source From Pubchem

Therapeutic Nucleic Acids Against Herpes Simplex Viruses (A Review)

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2023-11
DOI: 10.1134/s1068162023060067

Modified and Unmodified mRNA: For What Purpose?

Publication Name: The Marathon of the Messenger
Publication Date: 2023
DOI: 10.1007/978-3-031-39300-6_10

Time-resolved single-cell RNA-seq using metabolic RNA labelling

Publication Name: Nature Reviews Methods Primers
Publication Date: 2022-09-29
DOI: 10.1038/s43586-022-00157-z|10.1038/s43586-022-00171-1

Total RNA Synthesis and its Covalent Labeling Innovation

Publication Name: Topics in current chemistry (Cham)
Publication Date: 2022-02-26
DOI: 10.1007/s41061-022-00371-z

Probing the function of long noncoding RNAs in the nucleus

Publication Name: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology
Publication Date: 2020-02-06
DOI: 10.1007/s10577-019-09625-x