5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine|01544|103285-22-9

5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine

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Sku CI01544_5_G
Chem Impex
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Product Information

Product Name
5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine
Brand Name
Chem Impex
Product Number
01544
CAS
103285-22-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11039002
IUPAC Name
1-(2R,3R,4R,5R)-5-bis(4-methoxyphenyl)-phenylmethoxymethyl-4-hydroxy-3-methoxyoxolan-2-ylpyrimidine-2,4-dione
InChI Key
MFDHAVFJDSRPKC-YXINZVNLSA-N
SMILES
COC@@H1C@@H(C@H(OC@H1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O

Application

5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine is widely utilized in research focused on:

Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of RNA oligonucleotides, allowing researchers to create custom RNA sequences for various applications in molecular biology.

Drug Development: It plays a crucial role in the development of RNA-based therapeutics, such as mRNA vaccines, by facilitating the incorporation of modified nucleotides that enhance stability and efficacy.

Gene Expression Studies: Researchers use this compound to study gene expression and regulation, as it can be incorporated into RNA probes that help in detecting specific RNA molecules in cells.

Biotechnology Applications: In the field of biotechnology, it is employed in the design of RNA interference (RNAi) molecules, which are essential for silencing specific genes in research and therapeutic contexts.

Diagnostics: The compound is valuable in the development of diagnostic tools, such as PCR assays, where modified nucleotides improve the sensitivity and specificity of the tests.