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Sku CI12376_5_G
Chem Impex
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Product Information

Product Name
Fmoc-3,5-diiodo-D-tyrosine
Brand Name
Chem Impex
Product Number
12376
CAS
212651-51-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
46737398
IUPAC Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
InChI Key
IKNWCIROCRMKAY-OAQYLSRUSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@H(CC4=CC(=C(C(=C4)I)O)I)C(=O)O

Description

Fmoc-3,5-diiodo-D-tyrosine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of iodine into peptide structures, which can enhance their biological activity.

Drug Development: Its unique properties make it valuable in the development of novel pharmaceuticals, especially those targeting thyroid-related conditions or cancer therapies, where iodine plays a critical role in the mechanism of action.

Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, which can improve targeting and efficacy in therapeutic applications.

Research in Molecular Imaging: Due to its iodine content, it is utilized in molecular imaging studies, helping researchers track biological processes in vivo, which is essential for understanding disease mechanisms.

Antibody Labeling: Fmoc-3,5-diiodo-D-tyrosine can be employed in the labeling of antibodies for diagnostic purposes, enhancing the sensitivity and specificity of immunoassays.